方法选用7株丝状真菌为转化菌株,利用液相色谱质谱联用技术对药物代谢产物进行检测。
Method Metabolites produced by 7 filamentous fungi screened were identified by liquid chromatography-tandem mass spectrometry (LC-MSn).
结论该方法灵敏、快速、简便、有效,适合于生物样品中的药物及其代谢产物的快速鉴定。
Conclusion This method is sensitive, rapid, simple, effective, and suitable for the rapid identification of drug and its metabolites in biologic samples.
综述了目前HPLC-NMR联用技术在药物代谢研究,天然产物分析以及食品分析等方面的应用。
The application of HPLC-NMR in drug metabolism, natural products analysis and food analysis were reviewed.
肝脏是大部分药物转化代谢的场所,一些药物在肝脏代谢时,其本身或其代谢产物可对肝细胞产生直接或间接的毒性损伤。
The liver is the majority of medicines transformation metabolism place, when liver metabolism, some medicines itself and its metabolite may have direct or the indirect toxic damage to the liver cell.
采用HPLC法测定血中恩诺沙星及其代谢产物环丙沙星的浓度,用统计矩原理处理药物浓度时间数据。
Concentrations of enrofloxacin and its metabolite ciprofloxacin in plasma were determined by HPLC and the concentration-time data were analyzed by statistical moment principle.
不幸的是,这个化学药物有毒性代谢产物,所以不能用在人身上。
Unfortunately, this chemical has toxic metabolites that prevents it from being used in humans.
不幸的是,这个化学药物有毒性代谢产物,所以不能用在人身上。
Unfortunately, this chemical has toxic metabolites that prevents it from being used in humans.
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