用非房室模型参数估算法计算药动学参数。
The pharmacokinetic parameters were calculated according to non - compartment model.
比较两组的药动学参数。
The pharmacokinetic parameters of the two groups were compared.
目的测定注射用甲磺酸帕珠沙星的药动学参数。
Purpose To study the pharmacokinetics characteristics of pazufloxacin in healthy volunteers.
不同性别受试者药动学参数的差异无统计学意义。
There is no significant difference in the pharmacokinetic parameters between female and male subjects.
目的考察中国癫痫患者卡马西平的群体药动学参数。
AIM To investigate the pharmacokinetic profile of carbamazepine (CBZ) in Chinese epilepsy patients.
两制剂主要药动学参数经统计学分析无显著性差异。
These main pharmacokinetic parameters obtained showed no statistically significant difference between 2 products.
目的：研究单剂量口服替米沙坦片的人体药动学参数。
Objective: To assess the pharmacokinetic profile of telmisartan tablets.
目的用迭代二步法估算肌注妥布霉素的群体药动学参数。
OBJECTIVE to estimate the population pharmacokinetic parameters of tobramycin by iterative two stage method.
结论尿药法估算去甲斑蝥素人体药动学参数取样方便，样本处理简单。
CONCLUSION it's suitable to estimate the pharmacokinetic parameters by urinary excretion method, with the merits of convenient sample collection and simply specimen disposal.
目的：测定国产与进口拉西地平片剂的血药浓度，进行药动学参数比较。
OBJECTIVE: To determine the blood concentration of domestic and foreign lacidipine tablets, and compare their pharmacokinetic parameters.
药物浓度对时间数据作房室模型和统计矩解析，并求出相应的药动学参数。
Analysis of the data was executed by compartmental model and statistical moment calculation from which pharmacokinetic parameters were obtained.
对臼-内酰胺类抗生素的新的药动学参数，“超过MIC的时间”进行评价。
Objective To evaluate the new pharmacokinetic parameter, the duration of time that serum concentrations exceed the MIC(T > MIC)for beta - lactams.
结论健康受试者单剂量口服马来酸氟吡汀胶囊的药动学参数与文献报道基本一致。
CONCLUSIONS the pharmacokinetic parameters of flupirtine maleate in healthy volunteers after an oral single dose of flupirtine maleate capsule is concordant with that of the literature.
方法采用LC-MS/MS法测定血浆中甲氯噻嗪的浓度并用非房室模型计算药动学参数。
The concentration of methyclothiazide in blood plasma was measured by an validated LC-MS/MS method and were assessed with non-compartment model to obtain the pharmacokinetic parameters.
采用固相萃取-高效液相色谱法测定大鼠血浆中药物浓度，计算药动学参数和生物利用度。
The blood samples were collected from the rats and the plasma concentration was measured by SPE-HPLC. The pharmacokinetic parameters and absolute bioavailability were evaluated.
结论本方法操作简便，测定结果准确可靠。药动学参数对开展进一步人体实验有参考意义。
Conclusions The method is simple and accurate, which could be used to study human pharmacokinetics.
结论磷霉素的主要药动学参数与国外相关报道一致，本实验结果为临床用药提供了参考数据。
CONCLUSION The pharmacokinetic data were similar to those published. The study provide a method for clinical research of fosfomycin.
本文经静脉注射测定了病人心律平药动学参数，并对口服心律平的给药方案个体化进行了研究。
The pharmacokinetic parameter of patients' propafenone was measured by intravenous injection and the dosage regimen individualization by oral administration was studied.
采用HPLC - MS测定人血浆中阿折地平浓度，并计算单次及多次给药后的药动学参数。
The azelnidipine concentration in plasma was determined by HPLC-MS and the pharmacokinetic parameters were calculated.
用高效液相色谱-质谱法测定血浆中纳美芬的浓度，并采用PKS药动学程序对试验数据进行处理，求算有关药动学参数。
A HPLC-MS method was used to assay the namefene concentration in plasma. The pharmacokinetic parameters were evaluated with PKS program.
本发明应用了药动学模型和药效学模型来确定最适的药物制剂和最适的施用参数。
A pharmacokinetic and pharmacodynamic model is employed to determine optimum drug formulations and optimum parameters for administration.
参数法包括十个药动学模型和三种药效学模型，可以同时求算药动学和药效学参数；
Parametric method which based on the theory of "effect compartment" suggested by Sheiner (1979) et al includes ten PK models and three PD models.
参数法包括十个药动学模型和三种药效学模型，可以同时求算药动学和药效学参数；
Parametric method which based on the theory of "effect compartment" suggested by Sheiner (1979) et al includes ten PK models and three PD models.
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