药代动力学的基本过程分为分配和清除量稀释。
The fundamental pharmacokinetic processes are dilution into volumes of distribution and clearance.
目的:观察法莫替丁对多潘立酮药代动力学的影响。
AIM: To study the effect of famotidine on the pharmacokinetics of domperidone.
目的:研究高脂食物对氨茶碱控释片药代动力学的影响。
The effect of high fat diet on the pharmacokinetics of theophylline from controlled release aminophylline tablets has been observed in six healthy volunteers.
该文回顾了中药药代动力学的研究方法,并着重介绍了一些新理论和新方法。
Research methods of herbal pharmacokinetics of traditional Chinese medicines, especially in current progress, are reviewed.
其次,分析药物药代动力学的改变程度是否与P -糖蛋白的遗传多态性有关。
The secondary objective was to determine whether the magnitude of the pharmacokinetic interaction was influenced by P-glycoprotein genetic polymorphism.
目的:以“证治药动学”假说为理论指导,探索中医“证”对药代动力学的影响。
Objective: Based on the new "theory of syndrome and treatment pharmacokinetics", the effect of "syndrome in traditional Chinese medicine" on pharmacokinetics was explored.
当手性药物以外消旋体供药用时,其对映体间就可能发生药效学和药代动力学的相互作用。
Pharmacological interactions between the enantiomers may happen when a chiral drug was used as its racemate.
目的研究家兔灌服柚汁后对卡马西平血药浓度及药代动力学的影响,为临床合理用药提供参考。
Objective To study the influence of grapefruit juice on the pharmacokinetics of carbamazepine in rabbits so as to provide reference for rational administration in clinical practice.
目的比较空腹和高脂餐后顿服胺碘酮的药代动力学变化,探讨饮食对胺碘酮药代动力学的影响。
Ojective To investigate the pharmacokinetics of amiodarone tablets administered once orally after fasting or taking fatty food.
D大鼠是药代动力学的动物实验理想动物,它有个体差异小、成本低、适合药代动力学重复采血的优点。
SD rats are ideal animal in clinical Pharmacokinetics research for its little individual difference, low cost, blood re-collectable.
药物对映体结构特异性对局麻药药代动力学的各个过程都有着很大影响,包括药物的吸收、蛋白结合率、代谢等。
The enantiomer-specific structure of local anaesthetics has large impact on the pharmacokinetic process of these drugs, including absorption, protein-binding ratio, metabolism, and so on.
本文综述了利塞膦酸钠的药理作用,药代动力学,临床应用和不良反应。
This article reviews risedronate sodium in its pharmaco-mechanism, pharmacokinetics, clinical application and adverse reaction.
基于以上所述,GACVS得出结论认为,最近的药代动力学和发育学研究结果并不支持疫苗所含硫柳汞(乙基汞)存在安全性问题的说法。
On the basis of the foregoing, the GACVS concluded that the most recent pharmacokinetic and developmental studies do not support concerns over the safety of thiomersal (ethyl mercury) in vaccines.
巴格列酮已经经过一系列临床前期药效药理学、安全药理学、药代动力学或毒性动力学和药物代谢研究的评估。
Balaglitazone has been evaluated in a series of preclinical efficacy pharmacology, safety pharmacology, pharmacokinetic/toxicokinetic, and drug metabolism studies.
目的:研究维拉·帕米在高血压患者的药代动力学及药效学。
OBJECTIVE: To study the pharmacokinetics and pharmacodynamics of verapamil in patients with hypertension.
目的:建立加兰他敏血浆药物浓度的HPLC - UV检测法,研究其在人体的药代动力学和相对生物利用度。
OBJECTIVE: to develop a HPLC-UV method to determine the concentration of galanthamine in human plasma and study its pharmacokinetic profiles and bioequivalence.
解释各种药物用于治疗的基层医疗条件的药效学和药代动力学。
Explain the pharmacodynamics and pharmacokinetics of a variety of drugs used to treat primary care conditions.
结论本方法简便快速,定量准确,适用于盐酸替扎尼定人体临床药代动力学和生物利用度的研究。
Conclusion This method is simple, rapid and accurate, and eligible for the study of pharmacokinetic and bioavailability of Tizanidine Hydrochloride.
其他要考虑因素有药物的药代动力学和药效动力学。
Other factors to consider include the pharmacokinetics and pharmacodynamics of the drug.
扼要介绍重组蛋白多肽类药物的临床药代动力学研究的内容、方法和特点。
The clinical pharmacokinetics on recombinant protein or peptides, including the methodology, contents, and characteristics were introduced in brief.
大多数药代动力学参数的个体间差异大于8倍。
The individual variation inmost of pharmacokinetic parameters is more than 8 folds.
本文综述了喹烯酮的药代动力学、毒理作用、药物残留、休药期和应用前景等内容。
Pharmacokinetics, toxicological functions, drug residue, withdrawal time and the application perspective are summarized in this article.
目的:比较丙戊酸钠栓剂与片剂的药代动力学特征。
Objective: to compared the pharmacokinetics of sodium valproate suppository with sodium valproate tablets.
结果与结论该方法特异性、线性及线性范围、灵敏度、重现性、回收率均可达到蛋白多肽药物药代动力学研究的要求。
Results and Conclusion The specificity, linear range, reproducibility and recovery for the method could meet the requirements for studying pharmacokinetics of bioactive proteins or peptides.
结果得到血管内给药二室模型药代动力学参数估算的电子计算机程序。
Results An electronic computer program for pharmacokenetic parameter estimation was gained, and was applied to the pharmacokenetic parameter estimation.
目的:研究氟尿嘧啶乙酸口服给药后的药代动力学。
Objective: To study the pharmacokinetics of fluorouracil acetic acid (FUAC) after oral administration.
过去12年来的临床和药代动力学研究显示了口服后血浆和组织内抗坏血酸的浓度是被严格控制的。
Clinical and pharmacokinetic studies conducted in the past 12 years showed that oral ascorbate levels in plasma and tissue are tightly controlled.
采用以氯唑沙宗为底物探针的药代动力学方法研究氟苯尼考对鲫鱼细胞色素P4502E1活性的影响。
The effect of florfenicol(FFC) on the activity of cytochrome P450 2E1 in Carassius auratus was evaluated by pharmacokinetics using chlorzoxazone(CZX) as a specific substrate.
采用以氯唑沙宗为底物探针的药代动力学方法研究氟苯尼考对鲫鱼细胞色素P4502E1活性的影响。
The effect of florfenicol(FFC) on the activity of cytochrome P450 2E1 in Carassius auratus was evaluated by pharmacokinetics using chlorzoxazone(CZX) as a specific substrate.
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