结论体外转染白喉毒素a基因可杀伤人肺腺癌细胞并降低人肺腺癌细胞的致瘤性。
Conclusion: Transfection of DTA gene in vitro may kill human lung adenocarcinoma cells and reduce the oncogenicity of human lung adenocarcinoma cells.
这可能也是IL—2基因修饰后其致瘤性下降的重要机制之一。
It may be one of mechanisms of decreased tumorigenicity of IL - 2 gene modified tumor cells.
转EM13组小鼠与未转染组小鼠的瘤体重量和血管密度无明显差别，说明转EM13基因对H22细胞的致瘤能力可能没有影响。
Mice inoculated with H22 cells which transfected with EM13 have no difference with the mice of non-transfected group, which suggests that EM13 gene has no effect on the tumorgenesis of H22 cells.
目的研究b 71基因转染小鼠el4淋巴瘤细胞的致瘤性，为制备基因转染瘤苗提供实验依据。
Objective to study the Oncogenicity of rat EL4 lymphoma cell transfected with gene B71 and to provide experimental basis for preparing tumor vaccine by transfected gene.
目的研究转人IL2基因对原代肾细胞癌(RCC)细胞致瘤性的影响，为RCC的基因治疗提供依据。
Objective to study the influence on tumorigenicity of human renal cell carcinoma (RCC) cells transduced with human IL 2 gene, and to intend in forming a basis for RCC gene therapy.
尽管整体心室壁厚度下降，但是特定区域的形态学改变和基因敲除小鼠的心室壁粘液瘤的形成一致。
Although heart wall thickness was reduced overall, specific areas exhibited morphological changes consistent with myxomatous degeneration in the walls of knockout hearts.
本研究的目的是对TIF3基因转化NIH3T3细胞的致癌能力和致瘤性进行鉴定。
The objective of this study is to confirm the oncogenic and tumorigenic potential of the transformed NIH3T3 cells transfection mediated with TIF3.
建立杂交瘤单抗亲和层析纯化抗原、抗原体外致敏淋巴细胞和RT-PCR克隆人抗体基因及噬菌体呈现技术构建人源抗体库的策略。
Strategy was established for construction of repertoire antibody library with affinity chromatography purifying antigen, antigen immunizing human lymphocytes, RT-PCR and phage display technology.
肿瘤是各种原因导致多基因突变累积和相互作用形成的基因网络调控的结果，通过干预致瘤因子可能达到治疗肿瘤或改变肿瘤特性的目的。
Tumors are the results of accumulation of multiple gene mutations and their interactions. So by the intervention on tumorigenic factors, we may cure tumors or change their properties.
肿瘤是各种原因导致多基因突变累积和相互作用形成的基因网络调控的结果，通过干预致瘤因子可能达到治疗肿瘤或改变肿瘤特性的目的。
Tumors are the results of accumulation of multiple gene mutations and their interactions. So by the intervention on tumorigenic factors, we may cure tumors or change their properties.
应用推荐