L127F突变可能为致病性突变，与严重的临床表型相关联。
The novel mutation L127F was considered as a pathogenetic mutation and associated with severe clinical phenotype.
TSC也可以通过发现TSC1或TSC2基因上的致病性突变而得到诊断。
TSC can also be diagnosed by finding a change in either the TSC1 or TSC2 genes.
结论该老年白内障患者MYH9基因未见致病性突变，其具有的严重临床表型可能与存在新的基因突变类型或新的致病基因有关。
Conclusions the presenile cataract with serious clinical entities may be resulted from a novel mutation or another novel pathogenic gene with MYH9? RD.
突变体1-40-271菌落呈白色，产孢与萌发均正常，但萌发后即便在人工疏水表面上也不能形成附着胞，且丧失了致病性；
A white colony mutant, 1-40-271, was normal in sporulation and spore germination, but defective in appressorium development and totally lost in pathogenicity.
动态的基因突变和基因重组被认为是流感病毒A的致病性和宿主趋向性改变的关键因子。
Dynamic gene mutation and the reassortment of genes have been considered as the key factors responsible for influenza a virus virulence and host tropism change.
观察还发现，该突变体完全丧失了致病性。
观察还发现，该突变体完全丧失了致病性。
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