自然杀伤细胞是一类与T细胞和B细胞不同的淋巴细胞,可在未被致敏的情况下破坏外来细胞(如肿瘤细胞)。
Natural killer cells, which are a class of lymphocyte distinct from t cells and B cells, destroy foreign cells (eg, neoplastic cells) even without prior sensitization.
已被抗原致敏的细胞毒性T细胞是效应细胞,在抗病毒免疫中起到特别重要的作用。
Cytotoxic t cells, after sensitization by antigen, are effector cells, especially important in antiviral immunity.
抗原与致敏的肥大细胞表面互相作用。
Antigen interacts with the surface of sensitized mast cells.
如果进行骨髓移植,就要马上做人淋巴细胞抗原分型,血液制品也是用得越少越好,以免致敏。
If bone marrow transplant is to be done, HLA typing of the family is done immediately and blood products are used as little as possible to avoid sensitization.
目的探讨肿瘤多肽致敏的白介素12 (IL 12 )基因修饰的树突状细胞(DC)对自发性肺转移癌的治疗作用。
Objective To investigate the treatment of spontaneous metastatic lung cancer by tumor antigen-pulsed, interleukin-12(IL-12) gene-modified dendritic cells (DC).
结论:在肿瘤免疫治疗中,脉冲致敏DC一定要用灭活的肿瘤细胞作为抗原刺激物,才能有效地完成抗原递呈功能。
Conclusion: DC with pulse sensitization should use deactivated tumor cells as antigen stimulator substance, then, effectively perform antigen-presenting function in immune treatment of antitumor.
图示接触性皮炎,由致敏淋巴细胞引起的IV型超敏反应,在接触致敏性物质几天后出现。
This is contact dermatitis, a form of type iv hypersensitivity in which pre-sensitized lymphocytes led to this inflammatory reaction a couple of days after contact with the offending plant material.
目的观察肿瘤细胞裂解物致敏树突状细胞(DC)对小鼠乳腺癌的治疗作用。
ObjectiveTo investigate the effect of dendritic cells (DC) sensitized by tumor cells lysates on the murine breast cancer.
目的研究抗原冲击致敏的脐血树突状细胞体外对肿瘤细胞的杀伤作用。
Objective To investigate the lethal effect of dendritic cell derived from cord blood sensitized by antigen impact on tumor cell in vitro.
目的研究致敏淋巴细胞对兔颅骨成骨细胞增殖、分化的作用。
Objective To study the effects of sensitized t lymphocytes on osteoblastic proliferation and differentiation.
方法采用急性粒细胞白血病细胞可溶性蛋白抗原致敏体外培养的DC,并通过MTT法测定CTL活性。
Methods The dendritic cells(DCs) were cultured in vitro and induced by SPA. The activity of CTLs was detected by MTT.
方法观察普乐林注射液对小鼠的急性毒性,对人红细胞的体外溶血作用,对豚鼠致敏性及免疫性溶血的影响。
Methods: The acute toxicity of Puerarin in mice, the haemolytic effect on human erythrocyte in vitro, hypersensitization and immunohaemolytic effect on guinea pigs were studied.
这项研究中,对注射了癌细胞的小鼠通过致敏原诱发肺部炎症,结果发现癌细胞肺转移增加了3倍。
The new mice studies showed that, in mice injected with cancer cells, allergen-induced pulmonary inflammation resulted in a greater than 3-fold increase in lung metastases.
结果盐酸雷莫司琼注射液对豚鼠无致敏作用,对家兔红细胞无明显体外溶血及致凝集作用,对家兔血管无明显刺激作用。
Results Ramosetron hydrochloride injection has no hypersensitivity to guinea pig, no hemolysis and agglomeration to red blood cells of rabbit, no obvious stimulation to blood vessels of rabbit.
目的:探讨致敏的树突状细胞(DC)激活的肿瘤浸润淋巴细胞(TIL)体外抗小鼠乳腺癌活性。
Objective: To investigate the activities of tumor infiltrating lymphocytes(TILs) stimulated by dendritic cells(DCs) on mouse breast cancer cells in vitro.
目的探讨人类白细胞抗原(hla)配型在致敏受者肾移植中的临床意义。
Objective To investigate the clinical implication of human leukocyte antigen (HLA) matching in sensitized recipients of renal transplantation.
本文采用补体致敏酵母菌血凝法,检测了被动吸烟对小鼠红细胞免疫粘附功能的影响。
In the present, the effect of passive smoking on red cell immune adherence (RCIA) of mice was analysed by red cell agglutination test of complement sensitized yeast.
采用骨髓嗜多染细胞微核实验、致敏实验、以及细胞毒性实验对复合材料进行生物相容性评价。
Biocompatibility of the composites was evaluated by mouse micronucleus test, guinea pig sensitization test, in vitro cytotoxicity test respectively.
在细胞培养上清和小鼠腹水抗体的检测中,其灵敏度比经典的醛化致敏血球提高4~8倍。
The sensitivity of the test was proved to be 4—8 times as sensitive as that of classical passive hemagglutination test.
结果骨髓瘤冻融物致敏DC诱导的自身T细胞对患者骨髓瘤细胞的杀伤率远大于非致敏dc。
Results Autologous t lymphocytes induced by DCs pulsed with myeloma lysates had stronger killing effect on myeloma cells than t lymphocytes induced by non myeloma antigen pulsed DC.
以大肠杆菌表达的传染性法氏囊病病毒(IBDV)衣壳蛋白vp2致敏绵羊红细胞,建立间接血凝试验(IHA)。
An indirect hemagglutination assay (IHA) was set up using sheep erythrocytes sensitized with capsid protein VP2 of infectious bursal disease virus (IBDV) which were expressed in Escherichia coli.
含药血清对致敏大鼠腹腔肥大细胞脱颗粒有明显抑制作用。
Moreover, the degranulation of peritoneal mastocyte in rats also be suppressed by the serum containing SCZ.
并可诱导自体混合淋巴细胞强烈增殖反应,极显著高于未致敏DC组,肝癌细胞裂解物组和对照组(P<0.01)。
Autologous lymphocytes proliferation was markedly enhanced in hepatoma cell lysates pulsed DC vaccines group than that in unplused DCs group, hepatoma cell lysates group and control group (P<0.01).
本文讨论了HMG7可能的应用价值,以及在人淋巴细胞体外致敏过程中应注意的几个环节。
The potential implications of HMG7 and some important procedures of in vitro immunization were discussed in the paper.
目的:研究多发性骨髓瘤(MM)患者肿瘤冻融物致敏的树突细胞(DC)能否诱导特异性细胞毒t淋巴细胞(CTL)反应。
Objective: to explore the specific cytotoxic t lymphocyte (CTL) response induced by DC pulsed with tumor lysates from multiple myeloma (MM) patients.
本实验显示新型根管充填剂复方牡蛎粉无细胞毒性、无基因毒性、无皮肤致敏性以及局部刺激性,具有良好的生物相容性。
The new root canal filling material showed no detected cytotoxic, genotoxic effect, potential of skin sensitization and topical irritation and has good biocompatibility.
方法:采用脐带血来源的单核细胞制备树突状细胞,体外经s- 180细胞肿瘤相关抗原(TAA)致敏后免疫小鼠,一周后接种s - 180细胞株。
Methods: DCs were derived from cord blood monocytes, then were pulsed by tumor associated antigen (TAA) extracted from human stomach cancer S-180 cell line.
结论造血干细胞移植后输注致敏供者的淋巴细胞能促进受者的免疫功能重建,并可减少GVHD的发生。
Conclusion Sensitized donor lymphocytes infusion after HSCT evidently promoted the immune reconstitution and reduced the incidence of GVHD.
然而,由于缺乏细胞抵抗肿瘤致敏修复装置,而导致癌变。
However, the absence of repair machinery makes the cells resistant to tumor sensitizing agents and result in malignant transformation.
然而,由于缺乏细胞抵抗肿瘤致敏修复装置,而导致癌变。
However, the absence of repair machinery makes the cells resistant to tumor sensitizing agents and result in malignant transformation.
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