本文综述了利塞膦酸钠的药理作用，药代动力学，临床应用和不良反应。
This article reviews risedronate sodium in its pharmaco-mechanism, pharmacokinetics, clinical application and adverse reaction.
目的总结帕米膦酸钠在成骨不全症中的应用经验。
Objective To summarize the experience of pamidronate for osteogenesis imperfecta.
结论帕米膦酸钠对成骨不全症有较好疗效，但需更多病例观察。
Conclusion Pamidronate therapy has a positive effect on patients with osteogenesis imperfecta, while this still remains to be demonstrated in more patients with osteogenesis imperfecta.
结果两例对帕米膦酸钠有较好耐受性，治疗随访期间未再发骨折。
Results No fracture and significant adverse reaction were seen during pamidronate therapy.
目的探讨伊班膦酸钠（艾本）联合化疗治疗骨转移癌的临床疗效。
Objective To study the curative effect of ibandronate combined with chemotherapy in the treatment of metastatic bone cancer.
结论羟乙膦酸钠对老年骨质疏松性骨折有明显促进愈合和恢复功能。
Conclusion Etidronate disodium can evidently hasten heal and functional recovery of senile osteoporosis fracture.
目的：探讨利塞膦酸钠治疗绝经后骨质疏松症的临床疗效，并评价其安全性。
Objective:To evaluate the effect and safety of oral administration of residronate sodium in treatment of postmenopausal women with osteoporosis.
目的观察伊班膦酸钠(艾本)联合化疗对乳腺癌骨转移的止痛效果和不良反应。
Objective To evaluate therapeutic effect and adverse effect of ibandronate combined with chemotherapy in breast cancer patients with bone metastases.
结论：伊班膦酸钠能有效缓解多发性骨髓瘤患者骨痛，降低血钙，治疗高钙血症。
Conclusion: Ibandronate can effectively relieve bone pain caused by Multiple Myeloma and drop serum calcium, to treat hypercalcemia.
结论：本方法提高了反应收率，降低了成本，简化了操作，是合成伊班膦酸钠的有效途径之一。
Conclusion: a low cost, high yield, and simple process for preparation of sodium ibandronate is provided.
他说，对于那些严重的骨质疏松患者来说，在婴儿期或青春成长末期不要使用静脉注射药物帕米膦酸钠。
He said that those with more severe OI, babies or adolescents at the end of their period of growth, would be better off using the intravenous drug pamidronate.
目的：研究帕米膦酸钠对聚乙烯微粒刺激破骨细胞功能的影响，间接探讨帕米膦酸钠防治人工关节无菌性松动的可能性。
Objective: To investigate the effects of pamidronate on the osteoclasts activated by the polyethylene particles and explore the preventing effect of pamidronate on the aseptic loosening of prosthesis.
方法：在化疗间歇期应用伊班膦酸钠治疗骨转移癌患者68例，观察骨痛、活动能力、骨转移病灶、血钙变化及不良反应。
METHODS: All 68 patients were treated with ibandronate during the intermission of chemotherapy. Bone pain, ADL, bone metastasis focus, change of serum Ca2 + level and side effect were observed.
羟乙膦酸钠用药组骨量明显高于去睾丸组（骨小梁面积百分率增加了92 %） ，达到年龄对照组的水平，但未达到基础对照组的水平。
Results Trabecular bone volume was remarkably reduced in ORX rats compare with aging control and was increased 92% compare with ORX group, but could not attain the level of the basal control.
目的：探讨膦甲酸钠与苦参素抗病毒序贯疗法治疗活动性肝硬化的临床疗效观察。
Objective: To observe the clinical efficacy of Foscarnet sodium combined with Kurorinone in the seriate treatment of activity liver cirrhosis.
目的评估膦甲酸钠联合人工肝支持系统治疗重型乙型肝炎的临床价值。
Objective To estimate the clinical value of combination of PFA with ALSS in the treatment of SHB.
研究肾移植术后巨细胞病毒（CMV）感染的诊断及预防性使用膦甲酸钠（PFA）治疗的疗效与毒副作用。
To study the diagnosis of cytomegalovirus (CMV) infection after renal transplantation and the effects and side effects of preventive use of foscarnet (PFA).
目的：探讨膦甲酸钠的临床疗效及毒副作用。
Objective: To study the clinical efficacy and safety of foscarnet sodium.
结论膦甲酸钠可以安全有效地治疗乙型重型肝炎，明显降低病死率。
Conclusion Foscarnet sodium can safely and effectively treat patients with severe hepatitis B and decrease the fatality of severe hepatitis B.
目的探讨膦甲酸钠治疗慢性重型乙型肝炎的疗效及其不良反应。
To observe the clinical effect and adverse effect of foscarnet sodium in treating patients with chronic severe hepatitis B.
膦甲酸钠是一种高效低毒的广谱抗病毒新药。
Trisodium phosphonoformate (PFA) is a broad spectrum antiviral drug with low toxicity.
目的评价泛昔洛韦、膦甲酸钠及氧化苦参碱的体外抗hbv作用。
Objective To determine and compare the anti-HBV effect of famciclovir, foscarnet and oxymatrine in vitro.
目的：观察和比较3%膦甲酸钠和0 1%无环鸟苷滴眼液治疗单纯疱疹性角膜炎的疗效和安全性。
Objective:Both efficiency and safety about 3% foscarnet sodium and 0 1% acyclovir eye drops on treatment of 164 cases of herpes simplex keratitis were observed and compared.
目的：观察和比较3%膦甲酸钠和0 1%无环鸟苷滴眼液治疗单纯疱疹性角膜炎的疗效和安全性。
Objective:Both efficiency and safety about 3% foscarnet sodium and 0 1% acyclovir eye drops on treatment of 164 cases of herpes simplex keratitis were observed and compared.
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