染料木素是一种天然的异黄酮,在体外通过活化膜纤维化跨膜转运调节氯离子通道增加上皮阴离子的转运。
Genistein, a naturally occurring isoflavone, augments in vitro epithelial anion transport via activation of the cystic fibrosis transmembrane conductance regulator chloride channel.
结论一定浓度的苦参素可以抑制肾小球纤维化,保护肾小球系膜细胞,而对系膜细胞的表型转化无明显作用。
Conclusion Certain concentration of oxymatrine can inhibit kidney fibrosis and protect mesangial cells, but have no effect on the phenotype of mesangial cells.
光镜下发现各级冠状动脉壁水肿,外膜及中膜局灶性坏死,外膜及其周围组织淋巴郁滞,后期出现结缔组织增生或纤维化;
Light microscopy showed edema in the arterial wall with local necrosis in the media and adventitia, and dilated lymph vessles and later fibrosis in the adventitia and perivascular tissues.
术后眼压升高,除滤过泡瘢痕化因素外与手术区滤过膜的纤维化增厚及虹膜周边前粘连导致房水滤过减少密切相关。
The increase of IOP after the NPTS is related to the fibrous thickening of the filtration membrane in the operation area and the peripheral anterior synechia.
模型组大鼠肾小管间质细胞增多,肾小管基底膜增厚皱缩,纤维化明显,随时间进展而加重;
The renal interstitial cells increased in rats of the model group with the basal membrane thickened and shrank as well as obvious fibrosis, which were aggravated with the time prolonging.
非穿透小梁手术组术区滤过膜发生纤维化增厚30例(54.5%),虹膜周边前粘连12例(21.8%)。
The filtration membrane at the operation area of 30 cases(54.5%) in the NPTS group was fibrously thickened and peripheral anterior synechia was found in 12 cases(21.8%).
在2个对在发生ESRD前进行肾活检患者的报道中,1名患者出现间质性肾炎,其他人出现肾小球系膜和间质纤维化。
In 2 reports of patients who underwent biopsies before developing ESRD, 1 patient had interstitial nephritis, and the other had mesangial and interstitial fibrosis.
循环儿茶酚胺升高对心肌细胞产生直接的毒性作 用、增加膜通透性和心肌纤维化,这些作用可引起细胞死亡。
The increase of circulating catecholamines exerts direct toxic effect on cardiac myocytes, increases membrane permeability and myocardial fibrosis;
循环儿茶酚胺升高对心肌细胞产生直接的毒性作 用、增加膜通透性和心肌纤维化,这些作用可引起细胞死亡。
The increase of circulating catecholamines exerts direct toxic effect on cardiac myocytes, increases membrane permeability and myocardial fibrosis;
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