正在进行以添加第三种药物的研究，即静脉注射的前列腺素类花青素。
Studies are underway investigating the addition of a third agent, the intravenous prostanoid epoprostenol.
前列腺素和白三烯是重要的免疫功能，平滑肌功能，血小板聚集和炎症。
Prostaglandins and leukotrienes are important in immune function, smooth muscle function, platelet aggregation and inflammation.
心脏交感神经去甲肾腺素转运蛋白功能异常对心力衰竭恶化、进展发挥重要作用。
Impaired function of cardiac sympathetic nerve NET in cases of heart failure may contribute to worsening of the patients condition and to the progression of heart failure.
应加强眼用抗细菌药、前列腺素类似物、糖皮质激素的专科用药管理，促进其合理使用；
It is necessary to strengthen specialty medication management of ophthalmic antibiotics, prostaglandin analogue and glucocorticoid so as to promote rational use of them.
本文介绍了前列腺素内过氧化物合酶2基因的结构、表达、调控机理及其与繁殖性能的关系。
In this paper, we briefly introduced the structure, expression, regulation mechanism of prostaglandin-endoperoxide synthase 2 gene and the relationship between this gene and reproductive performance.
前列腺素e_1对炎症效应细胞的抑制作用和对肺细胞的保护作用有显著的剂量-效应关系。
There are significant dose-response relationships for the inhibitory effect of PGE_1on inflammatory effector cells and the cytoprotective effect of PGE_1 on lung cells.
布洛芬抑制前列腺素的生成，并通过增强缺氧性肺血管收缩反应而改善了肺损伤时的气体交换。
The inhibition of prostaglandin production with Ibuprofen strengthened hypoxic pulmonary vasoconstriction thus improved pulmonary gas exchanges in acid lung injury.
环氧化酶-2（COX-2）是环氧化酶的诱导型，是催化花生四烯酸合成前列腺素的限速酶。
Cyclooxyenase-2 ( COX-2 ) is the induced subtype of cycloxyenase, which is the rate-limiting enzyme that catalyzes the arachidonic acid synthesizing into prostaglandin.
但随着研究的深入，发现两者生成的前列腺素的生物功能不仅更复杂，而且还存在着相互联系。
However, recent data show that the biological functions of prostanoids formed by the two enzymes are much more complex and interrelated than previously appreciated.
如果眼内压的下降仅因为前列腺素含量在小梁网里的变化，则间质金属蛋白的活性改变也将发现。
If changes in the trabecular meshwork were solely responsible for the decreases in IOP seen with prostaglandins, then changes in MMP activity would be expected.
感染引发早产的机制与前列腺素的合成、细胞因子的异常分泌、基质金属蛋白酶活性增加等有关。
The mechanism of premature delivery caused by infection involves in increased prostaglandin synthesis, abnormal secretion of cytokines and increased activity of matrix metalloproteinases.
本文主要以前列腺素受体为分类依据，综述各类受体的特性以及相关药物的临床应用和研究进展。
This review summarizes the properties of each type of prostaglandin receptor, and the clinical applications and research progress of drugs targeting their corresponding prostaglandin receptors.
目的探讨机械损伤对人皮肤角质形成细胞前列腺素e2 (PGE2)分泌的影响及其可能的机制。
Objective To investigate the effects of mechanical damage on prostaglandin E2 (PGE2) secretion in human skin keratinocytes, and explore its possible mechanism.
两组患者均给予糖尿病宣教、适量运动、饮食控制等常规糖尿病治疗，对照组给予前列腺素E1治疗；
Two groups were treated with diabetes missionary, regular exercise, dietary control and other conventional diabetes treatment, control group given prostaglandin E1 treatment factors;
前列腺素对身体有很多影响。一部分能引起疼痛和和受损组织的扩张。另一部分就是保护胃壁和肠道壁。
Prostaglandins have several effects on the body. Some cause pain and the expansion, or swelling, of damaged tissue. Others protect the lining of the stomach and small intestine.
目的研究静脉注射前列腺素E1（PGE1）能否阻止酸吸入性急性呼吸窘迫综合征（ARDS）的发生。
Objective The purpose of this study was to evaluate the effect of prostaglandin E1 (PGE1) on blocking the development of acute respiratory distress syndrome (ARDS) induced by acid aspiration.
结论塞来昔布可能通过抑制环氧化酶2活性，减少前列腺素e2在大脑皮质中聚集，而抑制VEGF的表达。
Conclusion Celecoxib may reduce the accumulation of prostaglandin E2 by inhibiting cyclooxygenase-2 activity, and thus inhibiting the expression of VEGF.
不过，酪氨酸激酶是直接参与还是通过前列腺素和一氧化氮合酶对糖尿病炎症产生反应的，我们目前还不知道。
However, the involvement of tyrosine kinase either directly or through the prostaglandins and nitric oxide synthase in response to inflammation during diabetes is not completely understood.
结论：生姜油对小鼠佐剂性关节炎有抑制作用，其抗炎作用的机制之一可能与抑制炎症局部前列腺素合成有关。
Conclusion: Ginger Oil has an improvement of adjuvant arthritis in mice and one of its possible mechanisms of action is inhibiting the generation of prostaglandin in the area of inflammation.
目的：探讨兔肺移植中前列腺素a1 (PGA1)在对供肺缺血再灌注损伤的保护作用及其可能的作用机制。
Objective: To investigate the protective effects of prostaglandin A1 (PGA1) on ischemia-reperfusion during rabbit lung-transplant, and explore its possible mechanism.
对于病人来说，疾病还没有得到良好的控制，目前正在进行有关第三种药物即静脉前列腺素类依前列醇的研究。
For patients whose disease is still not well-controlled, studies are underway investigating the addition of a third agent, the intravenous prostanoid epoprostenol.
在促炎症反应如内毒素、缺血再灌注损伤和免疫反应中，过量释放的细胞因子和前列腺素样物质可引起肝损伤。
During proinflammatory reactions such as endotoxemia, ischemia - reperfusion and immune reactions, excessive amounts of cytokines and prostanoids are released resulting in liver injury.
阿司匹林：乙醯水杨酸的俗称，1899年发现的一种有机化合物。系水杨酸和醋酸的酯，会抑制前列腺素的生成。
Aspirin: Common name of acetylsalicylic acid, an organic compound introduced in 1899. The ester of salicylic acid and acetic acid, it inhibits production of prostaglandins in the body.
目的：探讨血小板活化因子(PAF)对肾小球系膜细胞(GMC)合成前列腺素e2 (PGE2)的影响及其意义。
OBJECTIVE to explore the effect and significance of platelet activating factor (PAF) on prostaglandin E2 (PGE2) synthesis in rat glomerular mesangial cell (GMC) in culture.
目的系统评价前列腺素e1治疗慢性肾功能衰竭的疗效和安全性，为临床选用前列腺素e1治疗该病提供循证药学证据。
Objective to determine the effectiveness and safety of PGE1 in patients with chronic renal failure (CRF) and to provide the proof of evidence-based pharmacy.
一种可能的选择是米索前列醇的标示外使用，这是一种合成的前列腺素E1类似物，被核准用于防止和治疗胃肠道溃疡。
One possible option in this setting is the off-label use of misoprostol, a synthetic prostaglandin E1 analogue licensed for prevention and treatment of gastrointestinal ulcers.
前列腺素也可以造成心脏，肾和血液工作的更好。但是存在一个问题。阿司匹林会阻止所有前列腺素的运转，好的和坏的。
Prostaglandins also make the heart, kidneys and blood vessels work well. But there is a problem. Aspirin works against all prostaglandins, good and bad.
启动子的激活、高糖刺激、炎性因子、自由基、十二脂氧化酶、前列腺素E等多种因素的作用下，COX-2表达显著上调。
The interaction of promoter activity, stimulation of hyperglycemia, inflammatory factors, free radicals, 12-lipoxygenase, prostaglandin E and other factors induces the expression of COX-2.
拉坦前列腺素增加了房水流畅度(67%)，在给药1个小时内发生变化。而前列腺素e增加的房水流畅度较其少(13%)。
Latanoprost increased outflow facility (an increase of 67%), with changes occurring within 1 hour of receiving drug, whereas PGE caused less of a change in outflow (an increase of 13%) facility.
对血压、凝血能力、疼痛知觉和生殖机制有重要作用，但一种特定的前列腺素，在不同的组织中可以产生不同的甚至相反的效果。
They have important effects on blood pressure, blood clotting, pain sensation, and reproduction mechanisms, but one prostaglandin may have different and even opposite effects in different tissues.
应用推荐