目的利用大鼠异位心脏移植模型，探讨门静脉注射供体脾细胞诱导免疫耐受的机制。
Objective on the rat model of heterotopic heart transplantation, the mechanism of immune tolerance induced by portal venous injection of donor spleen cells was studied.
目的寻找骨髓源性肝干细胞的表面标记，进行定向分化及脾内移植研究。
Objective To identify the surface marker of bone marrow-derived liver stem cells, isolate the stem cells, and investigate the differentiation and intrasplenical transplantation of the stem cells.
结论：自体脾移植对维持机体的T细胞水平和增强机体的抗感染能力有益。
Conclusion Splenic autotransplantation can help body to maintain t cells level and to improve the anti-infection ability.
目的建立治疗性单克隆抗体溶液持续器官灌注模型，应用抗大鼠树突状细胞单克隆抗体(WZD)降低大鼠移植脾的免疫原性。
Objective To reduce immunogenicity of the donor spleen, a rat model of continuous perfusion of graft was established with therapeutic anti dendritic cells monoclonal antibody (WZD).
观察肝移植前后大鼠外周血细胞数、脾指数、门静脉压力以及脾脏组织形态学的变化。
The cell counts of peripheral blood and the morphological changes of spleen were observed before and after liver transplantation in hepatic cirrhosis rats.
目的探讨输注同种脾细胞建立小鼠输血相关的移植物抗宿主(TA -GVHD)模型及其特点。
Objective To develop transfusion associated graft vs host disease (TA-GVHD) model by infusing allogeneic splenocytes.
目的观察白细胞介素2（IL-2）基因修饰的小鼠肝细胞经脾内移植后对肝脏免疫功能的影响以及对肝癌小鼠的治疗作用。
Objective To investigate the effects of intrasplenically transplanted , IL-2 gene-modified hepatocytes on the liver immune response and anti-tumor activity. Methods Murine fetal hepatocytes BNLCL.
移植ecp处理过的脾细胞令人信服的减少了GVHD相关死亡率；这和明显减低了肝、肠道、皮肤的GVHD评分有关。
The transfer of ECP-treated splenocytes convincingly reduced GVHD-associated mortality; this was associated with significant decreases in GVHD scores in the liver, gut, and skin.
方法在“细胞后环磷酰胺”方法的基础上输注供体脾细胞或去除了T细胞的供体脾细胞，然后进行皮肤移植。观察皮肤存活情况并探讨耐受形成机制。
Methods The donor spleen cells (SPC) or T cell depleted donor SPC were injected into the recipients which had been treated by"cells followed by CP system", after which skin grafting was performed.
结论：活化半相合混合骨髓移植方式可以降低GVHD反应，并与同基因和异基因脾细胞比例有关。
Conclusions: Halfmatched mixed BMT after activation could lower the GVHD reaction, which was relative to the ratio of syngeneic to allogeneic spleen cells.
目的：利用口服供者脾细胞延长受者大鼠的心脏移植存活时间，并探讨口服耐受的形成机制。
Objective To induce the prolongation of survival period of heart allografts in recipient rats by oral administration of donor spleen cells, and to study the mechanism of oral tolerization.
目的：在进行心脏移植手术的同时，经门静脉输注供体脾细胞诱导移植耐受，并探讨其耐受机制。
Objective: to induce cardiac transplantation tolerance in rat by perioperative injection of spleen cells into portal vein, and to study the mechanism concerning transplantation tolerance.
目的：在进行心脏移植手术的同时，经门静脉输注供体脾细胞诱导移植耐受，并探讨其耐受机制。
Objective: to induce cardiac transplantation tolerance in rat by perioperative injection of spleen cells into portal vein, and to study the mechanism concerning transplantation tolerance.
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