介绍了脑靶向空间稳定免疫脂质体制剂的研究进展。
Sterically stabilized immunoliposome for brain targeting can bring drugs into brain directed by specific monoclonal antibody.
咖啡酸甲酯和3,4 -二乙酰基咖啡酸能突破血脑屏障具有脑靶向性特点。
Methyl ester of caffeic acid and 3, 4-diacetyl-caffeic acid can cross the BBB and can thus be used as brain targets.
本研究建立的离体牛嗅黏膜模型实验手段简便，适用于经鼻脑靶向给药系统的体外评价。
The in vitro model would be useful for the evaluation of the intranasal delivery system for brain targeting.
结论鼻腔给药能够实现药物给药途径上的脑靶向，药物经脂质体包载后能明显增加其脑摄入，提高药效。
CONCLUSION Nasal administration is a better way to target the brain, and the brain uptake of drug modified with lioposomes would be increased, the pharmacodynamics would be improved.
目的构建以乳铁蛋白作为靶向功能基、可生物降解聚合物泡囊为载体的脑靶向递药系统，并对其脑部递药特性作出药效学评价。
OBJECTIVE to prepare a novel brain targeting system, lactoferrin conjugated self-assembled polymer vesicles (Lf-PVs), which the brain delivery property had been evaluated in vivo.
现从药物由鼻腔到脑的转运方式、影响因素、剂型、评价方法以及增强脑靶向性的方法等方面，对近年来鼻腔给药脑靶向性的研究进展进行综述。
Advances on drugs transport pathway from nasal cavity to brain, factors affecting the transport of drugs, types of dosage forms and evaluation tools of the brain-targeted nasal delivery system we...
对这些转运蛋白的研究使人们能深入地解析药物在血脑脊液屏障上的动态，更有效地调控药物转运行为，指导脑靶向与非脑靶向药物的研发设计。
Study on these transporters could attribute to elucidate the action of the drug at the BCSFB, regulate the drug transport behavior and guide the research & d…
目的：检测脑源性神经营养因子(BDNF)靶向药物对阿耳茨海默病(AD)转基因鼠的治疗作用。
Objective: to prepare a targeting drug for brain-derived neurotrophic factor (BDNF) and study its therapeutic effect in Alzheimer's disease (AD) transgenic mice.
目的：对小细胞肺癌的化疗、放疗、预防性全脑放疗及靶向治疗等方面的进展进行探讨。
OBJECTIVE: To discuss the progress in the chemotherapy, radiotherapy, preventive radiotherapy of whole brain, targeted therapy etc. for small cell lung cancer (SCLC).
将经过基因改选的干细胞注入癌症患者的大脑内，干细胞会将脑内的不活跃的抗癌药物转变为可以消灭肿瘤的、强有力的、靶向明确的抗癌剂。
GENETICALLY modified stem cells are to be injected into the brains of cancer patients, where they will convert an inactive cancer drug into a potent and targeted tumour-killing agent.
将经过基因改选的干细胞注入癌症患者的大脑内，干细胞会将脑内的不活跃的抗癌药物转变为可以消灭肿瘤的、强有力的、靶向明确的抗癌剂。
GENETICALLY modified stem cells are to be injected into the brains of cancer patients, where they will convert an inactive cancer drug into a potent and targeted tumour-killing agent.
应用推荐