目的:制备美洛昔康肠道内两次脉冲释药系统,并考察其体外释放影响因素。
Objective: To investigate two-pulse release tablets in intestinal tract of meloxicam, and to establish the method of drug release.
结论:通过调整处方和工艺,可以得到体外不同时间脉冲释药的盐酸地尔硫上(艹)下(卓)片剂。
CONCLUSION:The pulsatile release of ditiazem hydrochloride could be controlled by adjusting the composition of the outer shell materials and the manipulation condition.
脉冲释药系统是根据临床上治疗的需要,能定时释放药物的一种剂型,可用来治疗某些节律性发作的疾病。
Pulsed drug delivery system, which is capable of releasing drug after pre determined time to address clinically therapeutic requirements, is used to treat rhythm diseases.
结论:通过选择片芯中的崩解剂、调整包衣层组成和厚度,可以用包衣的方法得到不同时间脉冲释药的阿司匹林片剂。
Conclusion: the pulsatile release of aspirin can be controlled by selection of disintegrants of the core and changing composition and thickness of the coating film.
目的制备一种由溶蚀塞控制时滞的新型脉冲给药系统并对其体外释药行为进行评价。
AIM To develop a novel pulsatile drug delivery system of which the lag time is cont rolled by an erodible plug (EP) and evaluate its release characteristics in vitro.
通过吸水实验分析脉冲片的释药机制。
The pulsatile-release mechanism of the tablets was proved by the water take-up experiments.
通过吸水实验分析脉冲片的释药机制。
The pulsatile-release mechanism of the tablets was proved by the water take-up experiments.
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