埃伯哈特和他的同事们研究了恶性胶质瘤的细胞系以发现γ-内分泌酶抑制剂的影响,这种药物可阻断促使肿瘤增长的Notch受体途径。
Eberhart and colleagues studied glioblastoma cell lines to investigate the effects of a gamma-secretase inhibitor, a medication that blocks the Notch receptor, on tumor growth.
目的探讨蛋白酶体抑制剂MG- 132对体外人u87胶质瘤细胞增殖和凋亡的影响。
Objective to explore the effects of proteasome inhibitor MG-132 on proliferation, apoptosis of U87 glioma cells in vitro.
目的:探讨自噬抑制剂3-甲基腺嘌呤(3-MA)在H2O2诱导的神经胶质瘤U251细胞损伤过程中的作用。
AIM: To investigate the role of autophagy inhibitor 3-methyladenine(3-MA) in the injury of U251 glioma cells induced by H2O2.
目的:1、以人神经胶质瘤SHG细胞为研究对象,观察三种不同的葡萄糖苷神经酰胺合酶抑制剂d -PDMP、NB -DNJ、D - PPMP对SHG细胞增殖的影响。
Objective: 1, to study the effect of three different inhibitors of glycosphingolipid biosynthesis D-PDMP, D-PPMP and NB-DNJ on SHG cells growth.
目的:1、以人神经胶质瘤SHG细胞为研究对象,观察三种不同的葡萄糖苷神经酰胺合酶抑制剂d -PDMP、NB -DNJ、D - PPMP对SHG细胞增殖的影响。
Objective: 1, to study the effect of three different inhibitors of glycosphingolipid biosynthesis D-PDMP, D-PPMP and NB-DNJ on SHG cells growth.
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