一旦进入血液中，糖分就会与蛋白质融合产生糖基化终产物(缩写为ages)。AGEs导致胶原蛋白挥发变硬产生皱纹。
Once in the bloodstream, sugar bonds with protein and creates advanced glycation end products (aptly abbreviated AGEs), which cause collagen to become inflamed and stiff, leading to wrinkles.
胶原蛋白是一种纤维化蛋白质，是生物骨组织的重要组成部分，以胶原蛋白基质的形式存在。
Collagen is a fibrous protein that is a main component of living bone tissue, in which it forms a so-called collagen matrix.
透射电镜观察显示，哇巴因组大鼠心肌细胞肿胀，肌纤维断裂，Z线消失，线粒体增生肿胀，部分空泡化，细胞间胶原纤维增生。
Myofibrillar fragmentation, swelling of the cardiac myocytes, absence of the Z line, increases of the mitochondria and collagen fibers were found in ouabain group by transmission electron microscopy.
采用乙醇胺对胶原水解物酰胺化，采用二乙醇胺与甲醛的缩合物胺化，制得了阳离子蛋白填充剂。
A cationic protein filling agent has been prepared from collagen hydrolysate by amidation with ethanolamine and amination with diethanolamine-formaldehyde condensate.
结果表明胶原与透明质酸是逐层组装于电荷化的钛片表面。
The results showed collagen and hyaluronic acid were alternatively assembled on the charged surface.
免疫组化检测肝组织血管内皮生长因子(VEGF)、局部黏着斑激酶(FAK)、I型胶原和II I型胶原的表达。
The level of vascular endothelial growth factor (VEGF)? Focal adhesion kinase (FAK) and type I? III collagen in liver tissue were detected by.
目的探讨组织工程化胶原神经导管的构建及对外周神经缺损的修复。
Objective To investigate the construction of tissue engineering collagen nerve conduits and repair peripheral nerve defects.
牙本质基质蛋白(DMP)- 1是骨、软骨、釉质、牙骨质和牙本质生物矿化所必需的一种酸性非胶原蛋白。
Dentin matrix protein (DMP) -1 is an acidic non-collagenous protein that is necessary for the proper biomineralization of bone, cartilage, cementum, dentin and enamel.
结论利用壳多糖作为基质网架制备的组织工程化人工皮肤具有合成和分泌胶原蛋白的能力。
Conclusion the tissue engineering artificial skin which is reconstructed by chitosan as scaffold has the ability of synthesis and secretes collagen.
背景与目的：肺纤维化是一种病因复杂的疾病，以成纤维细胞过度增殖、胶原蛋白沉积为特征。
Background and Objective: The pathogenesis of pulmonary fibrosis is complicated, it is characterized with myofibroblast hyperplasia and deposition of collagen protein.
结论糖尿病小鼠创面外用GM-CSF凝胶，可诱导创面再上皮化和胶原蛋白合成，从而促进创面愈合。
Conclusion Local application of GM-CSF gel is able to promote diabetic wound healing in mice by inducing re-epithelization and collagen metabolism in the wound sites.
血清IV型胶原的测定对慢性肝病纤维化严重程度和预后的判断有重要临床意义。
The measurement of serum collagen IV is very important for assessment of grade of hepatic fibrosis and prognosis of chronic hepatitis.
目的研究金匮实脾法对实验性肝纤维化大鼠胶原纤维合成与降解的影响。
Objective To explore the influence of spleen-firming therapeutics on synthesis and degradation of collagen fibers of experimental hepatic fibrosis rat.
结论蚕丝和胶原海绵均可为组织工程化颌下腺体外构筑的支架材料，但胶原海绵更优于蚕丝。
Conclusion Both silks and collagen sponges have good biocompatibility with submandibular gland cells, and they can be used as the scaffolds for submandibular gland tissue engineering.
我们认为这种具有成纤维细胞增生因子活性的蛋白质可能就是在矽肺纤维化过程中刺激成纤维细胞增殖和胶原合成的调节因子。
We suggest that this protein may be the mediator which induces the proliferation of fibroblast and the synthesis of collagen during the process of silicosis.
目的探讨大鼠肝纤维化胶原生成细胞的来源。
Objective To study the sources of the collagen producing cells in rat liver fibrosis.
天狼星红胶原染色大鼠的心脏切片，观察药物干预对心肌纤维化的影响。
Collagen of the heart was stained by Sirius red to observe the effects of the drugs on myocardial fibrosis.
用组织化学染色(HE染色和MASSON染色)法检查确定标本组织的纤维化病理分期，在光镜下观察胶原的分布情况。
Histochemical stain (he and MASSON) was used to check and define the pathological stage of fibrosis of the specimen tissue, and observe the distribution of collagen under the light microscope.
目的：观察地塞米松在肺纤维化过程中对胶原积聚的抑制作用，探讨地塞米松治疗肺纤维化的机理。
Objective:To investigate the inhibitory effects of dexamethasone on collagen accumulation and discuss the mechanism of dexamethasone in treatment of pulmonary fibrosis.
方法采用原位胶原酶循环肝灌注法分离中国实验用小型猪肝细胞，海藻酸钠-氯化钡法微囊化。
Methods in situ recirculating collagenase perfusion method was used to isolate hepatocytes of Chinese experiment minipigs.
在微流道法形成的胶原和白蛋白格式化表面，细胞优先黏附于含胶原区域。
On the patterned surfaces generated from collagen and albumin solutions with microfluidic channels, cells preferentially localized in the collagen-coated region.
心肌纤维化是由于心肌间质胶原沉积增多，各型胶原比例失调所导致，可发生于多种心血管疾病。
Myocardial fibrosis is caused by overdeposition of myocardial interstitial collagen and proportion disorder of all kinds of collagen, and it occurs in many heart diseases.
心肌纤维化的改变采用心肌胶原形态定量分析。
The myocardial fibrosis was characterized by cardiac collagen morphological quantitive analyses.
方法：应用电子显微镜，网状纤维染色和ELISA方法检测大鼠肺纤维化的病理过程和胶原含量的改变。
Methods: Electron microscopy, reticulum fiber stain and ELISA test were used to observe the pathologic pro - cess of pulmonary fibrosis and to determine the change of collagen content.
所用实验动物的全层皮肤创伤在再上皮化、胶原合成和血管新生等方面有所增加，从而加速了创伤愈合的过程。
These animals showed accelerated healing of full-thickness skin wounds, with increased re-epithelialization rates, collagen synthesis, and angiogenesis.
结论实验组胶原分子聚合能力的改变，可能与腐殖酸对胶原分子中羟赖氨酰残基的糖苷化影响和胶原分子直径的影响有关。
Conclusions The influence of FA on the ability to collagen fibrillogenesis maybe caused by the changes of hydroxylysine glycosylation in collagen molecular and the diameter of collagen fibrils.
天狼星红胶原染色大鼠的心脏切片，观察药物干预对血管重塑和心肌纤维化的影响。
Stained the collagen in the slice of the heart by Sirius red to observe the effects of the drugs on vessel remodeling and myocardial fibrosis.
目的观察间质胶原酶(MMP - 1)表达质粒对大鼠肝纤维化的影响。
Objective To observe tile effects of MMP-1 (Matrix Metalloproteinase-1) expressing plasmid on rat liver fibrosis.
利用VG染色对肝脏胶原表达及纤维化程度进行评价。
VG staining was used to evaluate the expression of liver collagen and degree of liver fibrosis.
利用VG染色对肝脏胶原表达及纤维化程度进行评价。
VG staining was used to evaluate the expression of liver collagen and degree of liver fibrosis.
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