地特胰岛素—长效胰岛素类似物，作为基础胰岛素。
Levemir - Long-acting insulin analogue used as a basal (background) insulin.
但是，没有研究比较吸入式胰岛素与短效胰岛素类似物至今尚未公布。
However, no study comparing inhaled insulin with short-acting insulin analogues has yet been published.
甘精胰岛素是一种安全、有效的长效基础胰岛素类似物，用于糖尿病人的基础血糖控制治疗。
Insulin glargine is a safe, effective and long-acting insulin analogue. It can provide prolonged basal glucose control in patients with diabetes mellitus.
餐后预混胰岛素类似物治疗方案与基础胰岛素的2型糖尿病管理的模拟方案：以证据为基础的比较。
Prandial premixed insulin analogue regimens versus basal insulin analogue regimens in the management of type 2 diabetes: an evidence-based comparison.
然而，甘精胰岛素是经过修饰的人胰岛素(即胰岛素类似物)，可以提供更长时间的血糖控制(长效胰岛素)。
Insulin glargine, however, is a modified version of human insulin (an insulin analogue) that allows for the control of blood sugar for extended periods of time (a long-acting insulin).
因此胰岛素类似物的问世，尤其是白蛋白结合基础胰岛素类似物，使我们可以在2型糖尿病的超早期就开始胰岛素治疗。
Therefore, today, the advent of insulin analogues, especially the albumin-bound basal insulin analogues, has allowed us to start insulin at a very early stage in type 2 diabetes.
研究了一些胰岛素B链羧端肽段改变了的类似物与肝细胞及脂肪细胞的受体蛋白结合性质。
The receptor-binding properties of insulin and its analogs with modified C-terminal peptide sequence of the B-chain have been studied in liver cells and fat cells.
其次，新的基础类似物，无论是地特或甘精胰岛素，均已证实事实上并不增加体重，因为它们是基础胰岛素。
Secondly, the new basal analogues, whether it is detemir or glargine, have shown that they do not substantially increase weight because they are basal insulin.
目的：介绍胰岛素及其类似物的进展和临床应用概况，并评价其疗效与安全性。
Objective: to summarize the aspect of clinical usage and progress on insulin and insulin similitude, and to evaluate their clinical efficacy and safety.
甘精胰岛素是胰岛素的类似物，可以使患者在获得较好血糖控制的同时较少发生低血糖反应，但其价格相对较高。
Insulin glargine is an insulin analogue which has better glucose control and less hypoglycemic episodes, but has higher price.
二甲双胍和吡格列酮都是胰岛素增敏剂，因此这两类药物不会导致低血糖，而GLP-1类似物或DPP-IV抑制剂导致低血糖的概率也很低。
The metformin and pioglitazone are insulin sensitizers so they never lower you blood glucose below normal and the GLP-1 analogues or DPP-IV inhibitors also never lower your blood glucose below normal.
事实上，肠促胰岛素治疗不会发生胃排空，而GLP -1的类似物在治疗水平就会发生胃排空。
In fact gastric emptying does not occur with incretin therapy where as it does occur with GLP 1 analog therapy used at pharmacologic levels.
本发明涉及一种用基因串联的方法生产促胰岛素分泌肽glp -1(7 - 36)或GLP - 1类似物的方法以及由该方法生产的多肽。
The present invention relates to a method of producing glucagon-like peptide 1 (GLP-1) 7-36 and an GLP-1 analogue by consecutive genes, and peptide produced by said method.
本发明涉及一种用基因串联的方法生产促胰岛素分泌肽glp -1(7 - 36)或GLP - 1类似物的方法以及由该方法生产的多肽。
The present invention relates to a method of producing glucagon-like peptide 1 (GLP-1) 7-36 and an GLP-1 analogue by consecutive genes, and peptide produced by said method.
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