胰岛素受体底物2 (IRS - 2)是胰岛素受体激酶的主要底物之一(1)。
Insulin receptor substrate 2 (IRS-2) is one of the major substrates of the insulin receptor kinase (1).
目的：建立红细胞胰岛素受体酪氨酸蛋白激酶(IRTK)的活性测定法。
Objective: to establish a method of detecting insulin receptor tyrosine kinase (IRTK) activity from erythrocytes.
目的探索肝硬化时肝组织细胞胰岛素受体(IR)和酪氨酸蛋白激酶(TPK)含量的变化规律。
Objective to investigate the relationship between the expression of insulin receptor (ir) and the content of tyrosine protein kinase (TPK) in patients with hepatic cirrhosis.
本文对丁酸钠诱导分化的人白血病细胞株k- 562细胞的胰岛素受体酪氨酸蛋白激酶性及细胞内源性底物进行了研究。
In this paper, the tyrosine protein kinase activity of insulin receptor and its endogenous substrates were investigated on the human leukemia cell line K-562 differentiated by sodium butyrate.
目的探讨胰岛素受体酪氨酸激酶(TK)活性变化在胰岛素抵抗(IR)发生中的作用。
Objective to investigate the change of insulin receptor tyrosine kinase (TK) activity in the pathogenesis of insulin resistance (IR).
对丁酸钠转化前后的人红白血病细胞林k- 562的表面胰岛素受体数量、胰岛素受体酪氨酸蛋白激酶活性及细胞内源性底物进行了研究。
In this paper, the quantity of insulin receptors and the receptor tyrosine kinase activity and its endogenous substrates were comparatively studied in K-562 cells before and after transformation.
方法：对原发性高血压伴胰岛素抵抗患者胰岛素受体基因酪氨酸激酶域外显子17、18基因突变进行检测，并对突变的外显子进行核苷酸序列分析。
Methods: Using PCR SSCP, we detected the mutation of INSR tyrosine kinase domain exon 17 and exon 18 in 33 primary hypertension patients and 28 normal persons.
方法：对原发性高血压伴胰岛素抵抗患者胰岛素受体基因酪氨酸激酶域外显子17、18基因突变进行检测，并对突变的外显子进行核苷酸序列分析。
Methods: Using PCR SSCP, we detected the mutation of INSR tyrosine kinase domain exon 17 and exon 18 in 33 primary hypertension patients and 28 normal persons.
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