患有更严重类型的糖尿病患者其胰岛素分泌细胞存在问题。
Sufferers from the more severe form of diabetes have faulty insulin-producing cells.
纳入标准：干细胞向胰岛素分泌细胞诱导分化的研究进展。
Inclusive criterion: Articles about research progress of the differentiation from stem cells into islet-producing cells were selected.
探讨小鼠骨髓干细胞有无被诱导分化为胰岛素分泌细胞的可能性。
ObjectiveTo study whether the mouse bone marrow-derived stem cells have the possibility to be induced into insulin-secreting cells.
目的：探讨人骨髓源干细胞向具有功能的胰岛素分泌细胞分化的可能性。
AIM: To explore the possibility of differentiating functional insulin-producing cells from human BM-derived stem cells.
他推测，这是参与机制，激活细胞，触发免疫系统破坏的胰岛素分泌细胞。
He speculates that it is involved with the mechanism that activates cells that trigger the immune system to destroy insulin-producing cells.
【目的】探讨小鼠骨髓干细胞有无被诱导分化为胰岛素分泌细胞的可能性。
ObjectiveTo study whether the mouse bone marrow-derived stem cells have the possibility to be induced into insulin-secreting cells.
目的：本文就近年来干细胞诱导分化为胰岛素分泌细胞的研究进展做一综述。
OBJECTIVE: This article is a review about the research progress of the differentiation from stem cells into islet-producing cells.
研究者在哥伦比亚大学发现水平增加骨钙素的小鼠都刺激胰岛素分泌细胞的胰腺和增加胰岛素敏感性。
Researchers at Columbia University found that increased levels of osteocalcin in mice both stimulated the insulin-producing cells in the pancreas and increased insulin sensitivity.
研究者得出结论：这些发现表明人胚胎干细胞事实上可以在糖尿病的治疗上提供再生的胰岛素分泌细胞。
These findings suggest that human embryonic stem cells could, in fact, represent a renewable supply of insulin-producing cells for treating diabetes, the researchers conclude.
使用猪细胞的好处是这些细胞比来自人体胰腺的细胞更容易得到，胰腺是人体器官，人们从中提取胰岛素分泌细胞。
The advantage of using cells from pigs is that they would be much more readily available than cells from a human pancreas, the organ from which the insulin-secreting cells are taken.
它们可不附加任何基因而被诱导为胚胎样细胞，然后变为胰岛素分泌细胞，加里卡诺说此方法比其它方法更少的诱发恶性肿瘤。
They can be coaxed into an embryonic-like state without any additional genes, and after becoming insulin-producing cells, they produce less cancer than other methods, according to Gallicano.
此外，PDX-1可诱导非胰岛细胞如肝细胞、成肌细胞等向胰岛素分泌细胞分化，提示PDX-1在糖尿病的治疗领域有重要作用。
In addition, PDX-1 can induce non-islet cells such as liver cells, myoblasts to become insulin-producing cells, so PDX-1 has an important role in the treatment areas of diabetes mellitus.
胰腺的beta细胞感应葡萄糖浓度的变化，然后及时分泌适当的胰岛素进行调节。
Beta cells in the pancreas sense glucose levels, they sense the glucose levels changing and they secrete the right amount of insulin at the right time.
然而，有糖尿病的人，胰腺要么生成一点或根本没有生成胰岛素，或者是细胞没有正确的反应胰腺分泌的胰岛素。
In people with diabetes, however, the pancreas either produces little or no insulin, or the cells do not respond appropriately to the insulin that is produced.
当我们吃的时候，胰岛将自动的分泌足够的胰岛素，这些胰岛素将葡萄糖从血液中移进我们的细胞。
When we eat, the pancreas automatically produces the right amount of insulin to move glucose from blood into our cells.
苏打饮料中的大量糖分会增加人体的胰岛素水平，人们喝含糖的苏打软饮料时就增加了癌细胞生长的可能。胰岛素是胰腺分泌出来帮助人体代谢糖分的物质。
"The high levels of sugar in soft drinks may be increasing the level of insulin in the body, which we think contributes to pancreatic cancer cell growth," Pereira said in a statement.
经过改造的外分泌细胞除了生成胰岛素外，看起来很像beta细胞，并且停止制造典型的外分泌细胞蛋白。
Besides producing insulin, the transformed exocrine cells looked like beta cells and ceased making proteins typical of exocrine cells.
在制造的细胞之间点缀的是胰岛，分泌胰岛素与抗胰岛素直接进入血液。
Scattered among the enzyme-producing cells are the islets of Langerhans, which secrete insulin and glucagon directly into the bloodstream.
胰岛素是由胰腺中的特种细胞细胞分泌的。
Insulin is secreted by beta cells, specialized cells in the pancreas.
然而在这项新的研究中，研究人员能够从男性的睾丸组织提取细胞，分离干细胞，使之成为能够分泌胰岛素的胰岛细胞。
In the new study, however, researchers were able to take cells from men's testicular tissue, isolate stem cells, and turn them into insulin-secreting islet cells.
他们发现，在实验室这种天然物能刺激胰腺细胞分泌胰岛素。
They found it stimulated the secretion of insulin in pancreatic cells in the laboratory.
评估了大小胰岛细胞在低氧状态下的胰岛素分泌和模拟门静脉内移植环境量化了细胞死亡。
We assessed insulin secretion of large and small islets and quantified cell death during hypoxic conditions simulating the intraportal transplant environment.
巴西的一项研究显示，对1型糖尿病患者进行干细胞移植，可能会使胰腺重新开始分泌胰岛素。
Brazilian study has shown that stem cell transplants in patients with diabetes type 1 May kick start the pancreas into producing insulin again.
胰岛素是在人进食时胰腺的一种特殊细胞分泌的。
Insulin is secreted by special cells in the pancreas when a person eats.
本研究旨在研究增龄或限制能量摄入(CR)对胰岛细胞衰老及胰岛素分泌的影响。
We observed the influence of aging or caloric restriction (cr) on pancreatic beta cell senescence and its insulin secretion.
目的研究胰淀素对磺脲类降糖药刺激大鼠胰岛细胞分泌胰岛素作用的影响和机制。
Objective to study the effect and mechanism of amylin upon oral sulfonylurea drugs and its action to stimulate the islet cell secretion of insulin in rats.
在实验中，科学家们已经成功地诱导胚胎干细胞分化为心肌细胞和分泌胰岛素的胰腺细胞。
In the laboratory, scientists have been able to induce embryonic stem cells to develop into heart muscle cells or insulin-producing cells of the pancreas.
所构建的重组人胰岛素原基因能指导靶细胞随葡萄糖浓度的变化调节胰岛素分泌。
The cells combined human proinsulin gene has the ability of producing insulin with increase in glucose concentration in vitro.
结论：GLP鄄1可促进大鼠胰岛细胞胰岛素基因的表达和蛋白的分泌，对大鼠胰岛细胞亦有明显的促增殖作用。
Conclusion: GLP-1 can not only increase the insulin gene expression and insulin secretion, but also stimulate the proliferation of islet cells.
结论：GLP鄄1可促进大鼠胰岛细胞胰岛素基因的表达和蛋白的分泌，对大鼠胰岛细胞亦有明显的促增殖作用。
Conclusion: GLP-1 can not only increase the insulin gene expression and insulin secretion, but also stimulate the proliferation of islet cells.
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