目的：分析中国人遗传性非息肉病性大肠癌(HNPCC)家系的临床特征并检测这些家系中M3胆碱能受体基因(A)8区的突变情况。
Objective: to characterize the clinical features of Chinese HNPCC families and to screen the mutations of a poly (a) 8 tract in M3 cholinergic receptor gene in these families.
常见副反应为胆碱能作用、嗜睡、体重增加和一过性肝酶升高等。
The common adverse effects included cholinergic effects, drowsiness, weight gain, and transient increase of liver enzymes.
结论雌激素补充治疗能选择性影响基底前脑各亚区NOS和胆碱能神经元，并有可能影响学习和记忆能力。
Conclusion estrogen replacement can selective effect on the different basal forebrains subregion NOS and cholinergic neurons, and may concern ability of learning and memory.
目的：观察三七总皂苷(PNS)对老年性痴呆(AD)大鼠模型大脑胆碱能神经病理损害的保护作用。
Objective: to observe the protective effect of Panax notoginseng saponins (PNS) against pathological lesion of cholinergic neuron in rat model with Alzheimer's disease (AD).
目的探讨选择性破坏胰腺A细胞的模型大鼠胆碱能神经元的变化。
Objective To study the relationship of the injury of islet A cell and cholinergic neurons in rat.
目的设计、合成并筛选具有胆碱能活性，且对M1受体有选择性的莨菪烷衍生物。
OBJECTIVE to synthesize and screen tropane derivatives with cholinergic activity and subtype-selectivity of M1 receptor.
老年性痴呆患者除有学习记忆障碍外，亦发现脑内有铝聚集，有神经纤维缠结及中枢胆碱能神经功能低下等变化。
It is also discovered that Alzheimer's disease has similar symptoms such as learning and memory impairment, functional decrease of central cholinergic nerve, NFTs and gathered aluminum in the brain.
结论：血管性痴呆大鼠海马胆碱能神经元减少，空间记忆能力下降。
Conclusion The number of cholinergic neurons and abilities of learning and memory of vascular dementia rats are decreased.
胆碱能神经及其受体的变化在慢性阻塞性肺疾病(COPD)的发病过程中起重要的作用。
The changes of cholinergic nerve and its receptors play an important role in the course of chronic obstructive pulmonary disease (COPD).
新型选择性抗胆碱能药物作为支气管扩张剂在COPD治疗中发挥了重要的作用。
As bronchodilators, new type selective anticholinergics play an important role in the treatment of COPD.
本文探讨了脑源性神经营养因子、神经生长因子对体外长期培养的胚基底前脑胆碱能神经元是否具有延缓退变的作用。
The delaying effects of BDNF and NGF on the degeneration of the long term cultured embryonic basal forebrain cholinergic neurons in vitro were studied.
目的探讨针刺对实验性血管性痴呆（VD）大鼠中枢胆碱能神经元的影响。
Objective It is to discuss the influence of electroacupuncture on central cholinergic neurons of rats with experimental vascular dementia(VD).
中枢胆碱能系统参与调节哺乳动物的神经元兴奋性、皮质可塑性以及学习记忆过程，与脑认知功能密切相关。
It is generally agreed that the central cholinergic system plays an important role in learning and memory processes.
结论TS G可明显改善模型动物胆碱能系统的损伤，对于老年性痴呆的治疗有重要意义。
CONCLUSION TSG significantly improved the cholinergic damage in model rats, and it may play an important role in Alzheimer's disease therapy.
[导读]口服抗胆碱能治疗和注射A型肉毒杆菌毒素与急迫性尿失禁每日发作频率降低程度相似有关。
Oral anticholinergic therapy and onabotulinumtoxinA by injection were associatedwith similar reductions in the frequency of daily episodes of urgency urinary incontinence.
结论BPH梗阻性逼尿肌不稳定与逼尿肌胆碱能神经密度降低(去神经)程度有关。
Conclusion detrusor instability secondary to BPH obstruction is related to the decrease of cholinergic innervation density in the detrusor muscles.
结论BPH梗阻性逼尿肌不稳定与逼尿肌胆碱能神经密度降低(去神经)程度有关。
Conclusion detrusor instability secondary to BPH obstruction is related to the decrease of cholinergic innervation density in the detrusor muscles.
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