而在神经与肌肉之间充当“信使”的是一种叫做乙酰胆碱酯的酶，神经毒气正是通过抑制这种酶的工作来发挥作用的。
The gas inhibits acetylcholinesterase, an enzyme responsible for the breakdown of a chemical messenger responsible for muscle control, which is how it causes much of its ill effects.
研究人员将变异酶、少量的神经毒气和乙酰胆碱酯酶一同放置于试管中。
The mutated enzymes were then put in a test tube with a small amount of nerve agent and the acetylcholinesterase.
如果乙酰胆碱酯酶能够正常工作，那么就意味着新的变异酶成功地降解了神经毒气。
If the acetylcholinesterase continued to function normally, Tawfik concluded that the mutated enzyme had successfully degraded the nerve agent.
在这样的情况下乙酰胆碱酯酶将以简单扩散的方式进入唾液，因此它的活性必将和唾液流量速率相关。
However, under these circumstances cholinesterase would enter the saliva by simple diffusion and therefore activity should be correlated with salivary flow rate.
这些药物通过抑制在神经肌肉接合部位水解乙酰胆碱的乙酰胆碱酯酶的活性而发挥效应。
These drugs exert their effect by inhibiting the activity of acetylcholinesterase, the enzyme that hydrolyzes acetylcholine in the neuromuscular junction.
随着聚乙二醇基链长的增加，药物对乙酰胆碱酯酶抑制活性依次减弱。
With an increasing chain length of polyethylene glycol group linked on niclosamide, the inhibitory effects weakened.
乙酰胆碱酯酶，兔抗电鳗，生物素。
结论：硝基苯具有神经毒性，能够抑制肝和脑乙酰胆碱酯酶活性，且表现为明显的剂量效应。
We concluded that nitrobenzol is neurovirulent and it is able to inhibit the activity of cholinesterase in both liver and brain which displays evident dosage effect.
本文利用酶抑制原理，采用植物酯酶和乙酰胆碱酯酶法检测有机磷农药残留。
This article was based on enzyme inhibition principle and used Plant-esterase and Acetylcholinesteras to determine organophosphorus residue.
本文研究了V类毒剂与乙酰胆碱酯酶的作用方式。
The mode of action of V-type organophosphate poisons on acetylcholinesterase has been studied.
所得提取物均对人血浆乙酰胆碱酯酶有不同程度的抑制作用。
There were also some different inhibition of these extracts on acetylcholinesterase activity.
它已被认为是抑制乙酰胆碱酯酶的酶。
It has been found to be an inhibitor of the enzyme acetylcholinesterase.
目的：探讨A型肉毒杆菌毒素(BTA)对豚鼠鼻黏膜腺细胞乙酰胆碱酯酶浓度的影响。
Objective: to investigate the effect of botulinum toxin type a (BTA) on the concentration of acetylcholinesterase in nasal glands of guinea pig.
通过分析鉴定VS的主要酶解产物，对VS与电鳐乙酰胆碱酯酶的作用方式进行了探讨。
Based on the identified products, the modes of the action of VS on torpedo acetylcholinesterase were discussed.
根据酶的来源可以分为：植物酯酶法和乙酰胆碱酯酶法。
Grounded on which the enzyme was extracted from, the major methods were: Plant-esterase and Acetylcholinesteras.
本论文的主要工作是基于等离子体聚合膜的优良性质，构建电位型的乙酰胆碱酯酶生物传感器和电流型的过氧化氢生物传感器。
In this paper, a potentiometric acetylcholinesterase biosensor and two kinds of ampermetric hydrogen peroxide biosensors have been developed based on plasma polymerized film.
丝氨酸蛋白酶和乙酰胆碱酯酶高效的不可逆抑制剂。
A potent irreversible inhibitor of serine proteases and acetyl choline esterase.
乙酰胆碱酯酶因其来源不同，其氨基酸顺序及空间结构也存在一定差异。
The amino acid sequences and structure of AChEs from animals are different from each other.
更多的研究表明乙酰胆碱酯酶抑制细胞的增殖是通过催化和降解乙酰胆碱的酶活性来实现的。
Further study showed that ACHE suppressed cell proliferation via its enzymatic activity of acetylcholine catalysis and degradation.
实验用乙酰胆碱酯酶组化方法对褐云玛瑙螺中枢内乙酰胆碱酯酶的分布进行了研究；
We studied the distribution of acetylcholinesterase (AchE) within the central nervous system of Achatina fulica by AchE histochemical method.
用途：第二代中枢性乙酰胆碱酯酶抑制剂，是一只具有高度选择性、可逆性治疗阿尔茨海默病（老年痴呆）的药物。
Usage: The second generation of central acetylcholinesterase inhibitor, used as a highly selective and reversible treatment of Alzheimer's disease.
有机磷农药生物传感器已有很多报道，其设计原理大多是基于乙酰胆碱酯酶的不可逆抑制作用。
The design theory of the organ phosphorus pesticide biosensor is based on the irreversible restrain of acetyl cholinesterase by the organ phosphorus pesticide.
本发明涉及从蒲公英属植物中分离得到的一个木质素酸以及该化合物的强效抑制乙酰胆碱酯酶活性。
The present invention relates to lignin acid which is obtained by being separated from taraxacum plant and the strong activity of the compound of inhibiting acetylcholinesterase.
了解乙酰胆碱直接产生的M、N 样作用、抗胆碱酯酶药间接产生 M、N 样作用方式。 自学胆碱酯酶水解乙酰胆碱的过程。
Understand the direct M and N effects of acetylcholine and indirect M and N effects of anti-cholinesterase Self-learn the process of hydrolysis of acetylcholine by cholinesterase.
本发明的化合物具有抑制乙酰胆碱酯酶的活性，可期待作为防治老年性痴呆的药物用途。
The compound can inhibit activity of acetylcholinesterase and is expected to be used as a drug for preventing and treating senile dementia.
本研究结果为从中草药中快速筛选乙酰胆碱酯酶抑制剂提供了方法和数据支持。
This study provided method and data support for rapid screening of AChE inhibitors from traditional Chinese medicines.
本文以近年来该领域的研究成果为基础，综述了有机磷农药对海洋动物乙酰胆碱酯酶的毒性效应。
Based on the previous reports in this field, the toxicity of organophosphorus pesticides to AChE in Marine animals is reviewed in this paper.
乙酰胆碱酯酶抑制剂，农业上用于杀虫剂，临床上用于治疗老年痴呆。
Acetylcholinesterase inhibitors can use as the pesticides and the medicine for the treatment of Alzheimer's.
本文利用簇合效应原理，合成了一些对乙酰胆碱酯酶抑制活性较好的化合物，为今后的研究工作提供了很好的基础，值得进一步深入开展这方面的研究。
In summary, we designed and synthesised some bivalent compounds as potential AChE inhibitors by cluster effect, the study provides a basis for the further related work and were worth further studying.
本文利用簇合效应原理，合成了一些对乙酰胆碱酯酶抑制活性较好的化合物，为今后的研究工作提供了很好的基础，值得进一步深入开展这方面的研究。
In summary, we designed and synthesised some bivalent compounds as potential AChE inhibitors by cluster effect, the study provides a basis for the further related work and were worth further studying.
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