目的研究川芎嗪脂质体在体外对肿瘤细胞的细胞毒作用和对多药耐药的逆转作用，并研究脂质体剂型对上述作用的影响。
Objective: to study the cytotoxic effect of ligustrazine liposomes on tumor cell in vitro and the reversing effect on the MDR, and explore the influence of dosage form on the above effects.
近年研究发现容积调控性氯通道与肿瘤细胞的增殖、侵袭、迁移、凋亡及多药耐药性等恶性生物学行为有关。
In recent years, it has been realized that volume-regulated chloride channels are closely associated with proliferation, invasion, migration, apoptosis and multi drug resistance of tumor cells.
目前的研究发现，有多类细胞色素P 450酶与肿瘤多药耐药的发生密切相关。
In recent years, researches found that there were many kinds of cytochrome P450 enzymes which related to multidrug resistance of tumor.
目的：研究瑞香狼毒（SC）小鼠药物血清与细胞毒化疗药物联合应用对K5 6 2 /VCR多药耐药细胞的协同抗肿瘤效应。
Objective:To study the synergistic antitumor effects of Stellera chamaejasme (SC) with cytotoxic chemotherapeutic agents on K562/VCR multi-drug resistance (MDR) cells.
逆转肿瘤细胞多药耐药旨在全部或部分恢复肿瘤细胞对化疗药物的敏感性，已成为肿瘤mdr研究的热点。
The aim of reversing MDR of gastric cancer cells is to entirely or partly recovery their chemotherapy to drugs, which has become a hot spot in solid tumor MDR research nowadays.
临床化疗失败的重要原因是肿瘤细胞对化疗药物产生多药耐药（MDR）。
Multidrug resistance to chemotherapeutic drugs is an important reason for clinical chemotherapy failure.
临床化疗失败的重要原因是肿瘤细胞对化疗药物产生多药耐药（MDR）。
Multidrug resistance to chemotherapeutic drugs is an important reason for clinical chemotherapy failure.
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