新城鸡瘟病毒修饰自体肿瘤细胞疫苗能增强患者免疫功能,对放射治疗有协同作用。
Conclusions New castle disease virus-modified autologous tumor vaccine (NDV-ATV) enhances the immunity in cervical carcinoma and synergistically with radiotherapy.
滤泡性B细胞淋巴瘤是一种非霍奇金淋巴瘤,肿瘤疫苗是治疗是根据肿瘤细胞的生物学特殊性。
The cancer vaccines rely on a biological quirk of follicular B-cell lymphoma, which is a type of non-Hodgkin's lymphoma.
结论建立稳定表达人MUC1T739小鼠膀胱癌细胞株和t739荷瘤小鼠模型,可用于肿瘤疫苗研究。
Conclusion T739 mouse bladder cancer cell lines and tumor-bear model expressing human MUC1 were successfully established for the development of tumor vaccines targeting MUC1.
目的:探讨尤文肉瘤细胞总RNA转染的DC疫苗体外诱导特异性抗肿瘤免疫的能力及临床初步应用的效果。
Objective:To observe the ability of DC vaccine transfected with tumor cell total RNA to induce specific antitumor immunity in vitro and the primary clinical application in Ewing sarcoma patients.
免疫治疗包括通过导入抗体或淋巴细胞或者通过肿瘤疫苗免疫接种的方式来控制免疫系统,使其能来识别和清除肿瘤细胞。
Immunotherapy involves the manipulation of the immune system - by introducing an antibody or lymphocytes, or immunization with a tumor vaccine - to recognize and eradicate tumor cells.
目的探讨利用杂交瘤技术制备肿瘤疫苗的方法,研究肺癌树突状融合细胞的生物学特征。
Objective To explore the established method of tumor vaccine generated by hybrid technique and study the biological characteristics of lung cancer-dendritic fusion cell.
目的探讨由动员人外周造血祖细胞体外培养扩增获得的树突状细胞(DC)的生物学特性,为临床应用肿瘤树突状细胞疫苗建立制备方法。
Objective to obtain dendritic cells (DCs) from peripheral blood stem cells and hematopoietic precursor cells in vitro, and assess the feasibility of clinical application of tumor vaccine.
目的:探讨负载肿瘤抗原的树突状细胞(DC)疫苗诱导的细胞毒性T淋巴细胞(CTL)的体外杀瘤作用及对荷瘤小鼠的治疗作用。
Objective: to explore the anti-tumor effects of cytotoxic of T-lymphocytes (CTL) induced by dendritic cells (DC) vaccine loaded with tumor antigen.
目 的观察体外构建的榄香烯复合瘤苗抗原-卡介苗 热休克蛋白70复合物(HTA-HSP70BCG)诱导 的树突状细胞疫苗 的抗肿瘤效应。
Objective To investigate antitumor effects induced by dendritic cells (DCs) pulsed with complex of tumor antigen from elemene-combo tumor cell vaccine-heat shock protein 70 of BCG (HTA-HSP70BCG).
现就国内外关于树突状细胞功能研究及基因修饰的肿瘤疫苗临床试验作一综述,以期对未来的研究有所帮助。
This paper overviews the current status of dendritic cell function studies and clinical trials on gene-modified DC vaccine, for the purpose of helping the future research.
因此,筛选并鉴定肿瘤B细胞表位对肿瘤疫苗设计具有重要意义。
Selection and identification of B-cell epitopes are important for tumor vaccine designing.
目前已经开发了很多基于树突状细胞的肿瘤疫苗,然而抗肿瘤效果受到实际操作中许多因素的影响,因此研究人员将目光投向新的疫苗制剂。
So, researchers have focused their eyes on some new vaccines. Exosomes are vesicles secrected by different kinds of cells, such as B lymphocytes, tumor cells as well as mast cells.
结论小鼠脾脏细胞体外诱导培养可生成大量功能成熟的DC,为进一步抗肿瘤疫苗的研究奠定了基础。
Conclusion the functional DC could be induced by amplification cultivation mice spleen derived mononuclear cells in vitro. It would be the foundation of further step to produce antitumor vaccine.
然后进行U 251细胞系中肿瘤干细胞的凋亡机制的探讨,从而为脑胶质瘤的防治及肿瘤疫苗的研制提供新的策略和分子靶标。
Then, based on U251 cell lines tumor stem cell apoptosis mechanism will be discussed. Accordingly provide new strategies for the therapy in glioma.
然后进行U 251细胞系中肿瘤干细胞的凋亡机制的探讨,从而为脑胶质瘤的防治及肿瘤疫苗的研制提供新的策略和分子靶标。
Then, based on U251 cell lines tumor stem cell apoptosis mechanism will be discussed. Accordingly provide new strategies for the therapy in glioma.
应用推荐