这些新发现对了解细胞的生长调控和肿瘤的靶向性治疗具有重要意义。
These new findings are very important in regulations of the cell growth and cancer targeting therapy.
肿瘤靶向基因治疗的主要目的是用靶向性的载体将治疗基因靶向传递到肿瘤细胞。
A major goal of tumor-targeting gene therapy is to transfer genes efficiently to tumor cells by targeted vectors.
文章简要综述了溶瘤病毒肿瘤治疗的靶向性、杀伤性、安全性和疗效监测。
In this review, tumor targeting, killing efficiency, safety and the evaluation of oncolytic viruses therapy are discussed.
病毒载体的靶向性问题是肿瘤基因治疗中的重要研究热点，靶向病毒载体是提高肿瘤基因治疗安全性和有效性的重要途径。
Vector tropism is a research hot spot in cancer gene therapy, and targeted viral vectors play a key role in the enhancement of safety and efficiency in cancer gene therapy.
结果：热敏脂质体有良好的热靶向性，在肿瘤治疗方面效果明显。
RESULTS: Enhanced thermal targeting delivery and antitumor activity of drugs by thermosensitive liposomes in combination with local hyperthermia are achieved.
这种靶向性的策略包括目的基因对肿瘤细胞的靶向转移，目的基因在肿瘤细胞中的特异表达，以及基因修饰细胞分泌的肿瘤靶向治疗分子。
This can be achieved by tumor targeted gene transfer or tumor specific gene expression, as well as secretion of tumor targeted therapeutic molecules by autologous normal cells.
然而，肿瘤基因治疗同样面临一个特殊问题即转基因特异性表达于肿瘤部位问题，靶向性基因转导依然是目前基因治疗的一大障碍。
However, gene therapy for cancer is also faced with a specificity problem: the specific targeting of transgene expression to the site of the tumour.
减毒鼠伤寒沙门菌由于具有肿瘤靶向性，能在肿瘤组织中复制并产生抗肿瘤效果的能力，使肿瘤治疗获得了新契机。
Considering its tumor targeting, replication in tumor tissues and anti-tumor effects, attenuated Salmonella typhimurium has offered a new approach to tumor therapy.
减毒鼠伤寒沙门菌由于具有肿瘤靶向性，能在肿瘤组织中复制并产生抗肿瘤效果的能力，使肿瘤治疗获得了新契机。
Considering its tumor targeting, replication in tumor tissues and anti-tumor effects, attenuated Salmonella typhimurium has offered a new approach to tumor therapy.
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