本文从肿瘤的异质性以及肿瘤与宿主相互作用的角度讨论了其肺转移提高的原因。
The paper discussed the reasons for the enhanced metastatic capactity from metastatic heterogeneity of neoplasm, tumor cell-host interactions.
大量事实表明，包括脑肿瘤在内，所有肿瘤细胞群落之间在形态和功能上存在很大差异，其异质性与肿瘤干细胞的分化潜能有关。
There is overwhelming evidence that the tumor clone including brain tumor is heterogeneous with respect to both morphology and function, which indicates differentiation potential of tumor stem cells.
目的：探讨用ATP生物荧光肿瘤体外药敏检测技术（ATP-TCA）研究膀胱癌药敏的异质性和个体化疗的可行性。
Objective:To investigate the heterogeneity of chemosensitivity in bladder cancer using an ATP-tumor chemosensitivity assay (ATP-TCA) and the feasibility of individual chemotherapy.
目的探讨用atp生物荧光肿瘤体外药敏检测技术(atp -TCA)研究大肠癌药敏的异质性和个体化疗的可行性。
Objective To investigate the heterogeneity of chemosensitivity in colorectal cancer using an ATP-tumor chemosensitivity assay (ATP-TCA) and the feasibility of individual chemotherapy.
目的：探讨用ATP生物荧光肿瘤体外药敏检测技术（ATP-TCA）研究乳腺癌药物敏感性的异质性以及个体化治疗的可行性。
Objective:To investigate the heterogeneity of chemosensitivity in breast cancer using an ATP-tumor chemosensitivity assay (ATP-TCA) and the feasibility of individual chemotherapy.
目的探讨免疫共沉淀法在肿瘤异质性蛋白质分子机制研究中的可行性，为肿瘤异质性研究建立一种新的方法。
Objective To explore a novel methodology for tumor heterogeneity research, we reveal the feasibility of using co immunoprecipitation in the protein molecular mechanism of tumor heterogeneity.
这种筛选方法，为只经过淋巴道转移的瘤株，找到了一个初步检测肿瘤有无异质性的简便方法。
This is a simple screening method to detect the heterogeneity for the tumour strain only with lymphatic metastasis.
由于肿瘤发生的复杂性及患者的异质性，往往要将基因治疗与其它疗法相结合才能收到满意的疗效。
Because of the complexity of tumors and heterogeneity of human, gene therapy is often needed to combined with other therapies to obtain good effect.
EGFR蛋白过表达和EGFR拷贝数改变的肿瘤内异质性无统计学意义。
Intratumoral heterogeneity of EGFR protein overexpression and EGFR copy number alteration was not significant.
对每个肿瘤三个不同区域进行免疫组化和银原位杂交，以判定HER2基因扩增的区域异质性和遗传异质性。
Regional and genetic heterogeneity of HER2 gene amplification was determined in three different areas of each tumor by immunohistochemistry and silver in situ hybridization.
拷贝数分析显示肿瘤具有异质性，具有异源性分化的恶性叶状肿瘤有不同的肿瘤演化。
Copy number analysis revealed intratumoral heterogeneity and evidence for divergent tumor evolution in malignant phyllodes tumors with and without heterologous differentiation.
这些发现有益于我们理解肿瘤异质性并揭示单个细胞行为的随机性促进了癌细胞群的表型平衡。
These findings contribute to our understanding of cancer heterogeneity and reveal how stochasticity in single-cell behaviors promotes phenotypic equilibrium in populations of cancer cells.
肿瘤异质性是通过测序7个肿瘤的两个不同区域来评估，包括异种分化肿瘤的非异源性和异源性成分。
Intratumoral heterogeneity was assessed by sequencing two separate areas in 7 tumors, including non-heterologous and heterologous components of tumors with heterologous differentiation.
理解肿瘤多样化是肿瘤异质性和癌症进化的长期挑战的问题。
Understanding tumor diversity has been a long-lasting and challenging question for researchers in the field of cancer heterogeneity or tumor evolution.
通过分析肿瘤细胞的密度及等位基因突变的几率来确定肿瘤异质性和等位基因特异性突变的不平衡性。
Tumor cellularity and mutant allele frequency were analyzed to identify tumor heterogeneity and mutant allele-specific imbalance.
通过分析肿瘤细胞的密度及等位基因突变的几率来确定肿瘤异质性和等位基因特异性突变的不平衡性。
Tumor cellularity and mutant allele frequency were analyzed to identify tumor heterogeneity and mutant allele-specific imbalance.
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