相对于原癌基因和肿瘤抑制基因。
Contrast with proto-oncogene and with tumor-suppressor gene.
肿瘤抑制基因促进肿瘤生长?
在固体肿瘤抑制基因转染,观察小鼠。
The inhibition of gene transfection on solid tumor was observed in mice.
主题词肿瘤抑制基因;
胶质母细胞瘤9号染色体肿瘤抑制基因的研究。
A study of tumor suppressor genes on chromosome 9 in glioblastomas.
TP53肿瘤抑制基因参与了多种细胞内过程。
The TP53 tumor suppressor gene is involved in a multiple cellular processes.
探讨肿瘤抑制基因对肺腺癌细胞生长的抑制作用。
To investigate the suppression effect of tumor suppressor gene in lung adenocarcinoma cells.
这种染色体异常使控制细胞生长的关键肿瘤抑制基因失活。
Such chromosomal abnormalities inactivate tumor - suppressor genes that are critical for controlling cell growth.
称之为肿瘤抑制基因的突变可以引起生长失去控制,从而可能导致癌症。
Mutations in so-called tumor suppressor genes can result in loss of growth control, which in turn may result in cancer.
他们发现当用DADS治疗时,有名的肿瘤抑制基因p53阻止了细胞循环 。
They found that the famous tumor suppressor gene, p53, arrested the cell cycle when DADS treatment was present.
一些小鼠还有肿瘤抑制基因p 53缺陷,这种缺陷突变存在与大约一半的人类肺癌。
Some of the mice also had defective versions of the tumor suppressor gene p53, which is mutated in about half of human lung cancers.
因此,XAF1是一个新的肿瘤抑制基因,有可能成为肿瘤治疗的新靶向基因。
Thus XAF1 is a new cancer inhibiting gene and may become a new target to treat carcinoma.
被该甲基化抑制的基因包括通过其它方式预防肿瘤生长与扩散的肿瘤抑制基因。
Genes suppressed by this methylation include tumor suppressors that would otherwise prevent cancer growth and spread.
结果表明肿瘤抑制基因CDKN2可望成为NSCLC基因替代治疗的候选基因。
The observations suggest that the tumor suppressor gene CDKN2 is a potential candidate for ge ne replacement therapy of NSCLC.
综述了一些癌基因、肿瘤抑制基因和DNA修复基因对细胞电离辐射敏感性的影响。
Reported effects of some oncogenes, tumour suppressor genes and DNA repair genes on sensitivity of cells to ionizing radiation are reviewed.
目的 从蛋白水平探讨口腔鳞癌组织中肿瘤抑制基因PTEN的表达及临床病理意义。
Objective To explore expression of PTEN in oral squamous cell carcinoma (OSCC) and its clinicopathological significance.
目的探讨肿瘤抑制基因杂合性缺失(LOH)在肝原发性淋巴瘤(PHL)发生中的作用。
Purpose To investigate the possible role of loss of heterozygosity (LOH) of tumor suppressor genes in the development of primary hepatic lymphoma (PHL).
UCSD研究者也对丢失肿瘤抑制基因的小鼠进行研究。肿瘤抑制基因可以阻止细胞生长。
The UCSD researchers also studied mice that were missing a tumor suppressor gene, which is a gene that ACTS to prevent cell growth.
基因组文库中分离到一个与人类肿瘤抑制基因QM具有同源性的基因,命名为OSQM1。
A gene homologous to the human putative tumor suppressor gene QM, designated OSQM1, was isolated from rice Oryza sativa l.
SIPA1在HCC中发挥肿瘤抑制基因的作用,且对抑制HCC的复发转移有重要作用。
SIPA1 probably inhibits the metastasis and recurrence of HCC as a tumor suppressor gene.
多数常见癌症中,肿瘤抑制基因FHIT的表达因受遗传或表观遗传因素的作用而受到抑制。
The tumor suppressor gene FHIT is inactivated by genetic and epigenetic changes in the majority of common human cancers.
虽然许多原癌基因和肿瘤抑制基因被广泛表达,这些基因的突变与特定的器官或细胞类型的癌有关。
Although many proto-oncogenes and tumor suppressor genes are widely expressed, the mutation of these genes is associated with cancer of specific organs or cell types.
这些观察提示突变的酪氨酸磷酸酶是肿瘤抑制基因,它调节的细胞通路可能会被利用到治疗干预中去。
These observations suggest that the mutated tyrosine phosphatases are tumor suppressor genes, regulating cellular pathways that may be amenable to therapeutic intervention.
原癌基因的突变导致的过度刺激细胞周期,而突变的肿瘤抑制基因,会导致在这一功能的控制过度活动。
Oncogenes are mutations that cause an excessive stimulation of the cell cycle, while mutations in tumor suppressor genes can result in a loss in function in controlling this excessive activity.
BRCA - 1相关蛋白(BAP1)是一种肿瘤抑制基因,约半数的间皮瘤中显示双等位基因失活。
BRCA-1-associated protein (BAP1) is a tumor suppressor gene, which shows biallelic inactivation in approximately half of all mesotheliomas.
运用这种新技术,可以在大约25,000个人类基因中鉴别出肿瘤抑制基因,并且显著加快研究进程。
With the new technique, it is possible to identify potential tumour-suppressor genes from among the approximately 25,000 human genes and accelerate research significantly.
TGF配体虽然在早期肿瘤中作为肿瘤抑制基因发挥作用,但其在进展期肿瘤中却变成有效的促转移因子。
TGF ligands act as tumor suppressors in early stage tumors but are paradoxically diverted into potent prometastatic factors in advanced cancers.
第10号染色体同源丢失性磷酸酶-张力蛋白基因(PTEN)作为肿瘤抑制基因,可以负性调节肿瘤细胞的生长。
As a tumor-suppressor gene, phosphatase and tensin homology deleted on chromosome 10 (PTEN) regulates negatively the growth of tumor cells.
一种由深圳赛百诺基因技术公司――一家中国公司,所使用的方法就是用正常的肿瘤抑制基因置换破损的肿瘤抑制基因。
One approach, used by Shenzhen SiBiono GeneTech, a Chinese company, is to replace broken tumour-suppressor genes with the correct version.
一种由深圳赛百诺基因技术公司――一家中国公司,所使用的方法就是用正常的肿瘤抑制基因置换破损的肿瘤抑制基因。
One approach, used by Shenzhen SiBiono GeneTech, a Chinese company, is to replace broken tumour-suppressor genes with the correct version.
应用推荐