这部分细胞被称为肿瘤干细胞。
肿瘤干细胞是肿瘤转移和复发的根源。
If the tumor stem cells have not been cleared, then relapse and metastasis may be inevitable.
目的介绍肿瘤干细胞在实体肿瘤中的研究进展。
Objective To summarize the status of tumor stem cells study in solid tumors.
而CD 166在大肠癌肿瘤干细胞中高表达。
CD166 has a high expression in colorectal cancer stem cells.
肿瘤转移与肿瘤干细胞的转移和归巢行为密切相关。
Tumor metastasis is closely related to metastasis and homing of tumor stem cells.
这些罕见的肿瘤干细胞亚群的发现将成为癌症研究的热点。
The discovery of rare subpopulations of cancer stem cells has indeed entirely changed the focus of cancer research.
本文从诊断、治疗和脑肿瘤干细胞三个方面概述了其进展。
This article review the progress from diagnosis, treatment and brain tumor stem cell.
但重要的是，脑肿瘤干细胞中这些分子呈现显著的过表达。
Importantly, a significant over-expression of these molecules were found in the brain tumor stem cells.
“肿瘤干细胞是指启动整个肿瘤生长的细胞，”Ince解释。
"Tumor stem cells are cells that can initiate a whole tumor," Ince explained.
CD44及内皮素转化酶在肺癌肿瘤干细胞中的表达具有意义。
Expressions of CD44 and endothelin-converting enzyme in lung cancer stem cells are of significance.
巢蛋白、波形蛋白和CD 117在神经系统肿瘤干细胞中有表达。
Nestin, vimentin, and CD117 express in cancer stem cells of the nervous system.
我们培养出一个肿瘤干细胞模型用来研究人类结直肠癌(CRC)。
Here we developed a CSC model for the study of human colorectal cancer (CRC).
从同一组织研究正常干细胞和肿瘤干细胞，肿瘤的个体已经初见光芒。
Studies of normal and cancer stem cells from the same tissue have shed light on the ontogeny of tumors.
现在研究人员发现肿瘤干细胞在加热以后其惊人的抗辐射能力急剧下降。
Now researchers have shown that this extraordinary radiation-resistance among tumor stem cells can be dramatically lowered by heating them up.
目的：探讨卡莫司汀对人脑肿瘤干细胞在细胞增殖及细胞周期方面的影响。
Objective To investigate the effects of BCNU on the proliferation and cell cycle of stem cells from human brain tumor.
这些发现表明肿瘤干细胞基因标签可用于鉴别具有高复发和转移风险的患者。
These findings suggest that this cancer stem cell gene signature may be used to identify patients at the highest risk for disease recurrence and metastasis.
起初肿瘤变小了，但是其中的肿瘤干细胞存活下来，最后形成新的侵袭性更强的肿瘤。
The tumor shrinks at first, but stem cells within the tumor survive and eventually seed the growth of new, more aggressive tumors.
干细胞研究极大地促成了肿瘤学另一个新领域的研究，即从各种肿瘤中分离并鉴定肿瘤干细胞。
Stem cell research has greatly contributed to the field of oncology with the identification and isolation of cancer stem cells from a variety of tumors.
将肿瘤干细胞作为放射治疗的切入点，针对其放射生物学行为制订对策，才能从根本上解决问题。
Taking radiotherapy of tumor stem cells as a contact point, strategy designed by radiobiology can essentially solve this problem.
间质干细胞从骨髓到达肿瘤部位，为肿瘤干细胞产生了一个栖身处所，便于肿瘤干细胞复制、增殖。
These cells are drawn from the bone marrow to the cancer and create a "niche" for the cancer stem cells, allowing them to replicate.
肿瘤干细胞的概念对于我们理解肿瘤生物学和构思针对这类细胞的靶向治疗来说，可能有着更加深远的意义。
The concept of cancer stem cells may have profound implications for our understanding of tumor biology and for the design of novel treatments targeted toward these cells.
阻断这些细胞因子信号，研究人员希望能通过靶向肿瘤干细胞群，成功地提供一种更有效的乳腺癌治疗手段。
By blocking these cytokine signals, researchers hope that they can successfully target the cancer stem cell population providing a more effective treatment for breast cancer.
背景：肝癌的转移复发被认为可能存在有肿瘤干细胞，后者在肿瘤细胞中数目极少，使得临床鉴别存在一定困难。
BACKGROUND: There may be tumor stem cells during metastasis and recurrence of liver cancer. The number of tumor stem cells is very few, so it is difficult to be identified.
本文综述具有科学证据支持并与肿瘤进展相关的肿瘤干细胞模型，同时探讨该模型的在实验应用和临床治疗的价值。
In this review we present scientific evidence supporting the cancer stem cell model of tumor progression, and discuss the experimental and therapeutic implications.
肿瘤干细胞与正常干细胞具有许多相似的特征和信号通路，因而认为正常干细胞是肿瘤干细胞起源的最佳候选细胞。
Normal stem cells are regarded as an ideal candidate for the origin of cancer stem cells when take similar characters and signaling pathways between them into consideration.
“直到目前，大部分药物实验只在标准的肿瘤细胞系中测试，而这些细胞系很少含有肿瘤干细胞，”Ince解释到。
"Until now, most of the drug testing had been done on standard tumor cell lines that only have very few tumor stem cells in them," Ince explained.
肿瘤干细胞不仅保留了正常干细胞的性质，并且具有自身的特点，对其展开的研究，将为肿瘤的靶向治疗开辟新的途径。
Cancer stem cells not only reserve the characteristics of stem cells, but also have their own nature. To study the cancer stem cells will give a new therapeutic approach for targeting tumor cells.
肿瘤干细胞不仅保留了正常干细胞的性质，并且具有自身的特点，对其展开的研究，将为肿瘤的靶向治疗开辟新的途径。
Cancer stem cells not only reserve the characteristics of stem cells, but also have their own nature. To study the cancer stem cells will give a new therapeutic approach for targeting tumor cells.
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