RNA干扰是肿瘤基因治疗的有效手段。
针对CXCR4靶向治疗将成为肿瘤基因治疗研究的新热点。
CXCR4-targeted therapeutic approaches will become a new hot point in the research of tumor gene therapy.
本文对超声微泡造影剂在肿瘤基因治疗中的应用及进展进行综述。
The application and process of ultrasound microbubbles in gene therapy of tumor were reviewed in this article.
研究结果表明，该基因可用于多种肿瘤的诊断标志基因，也可以作为肿瘤基因治疗的靶基因。
The research result shows that: it can be applied to diagnostic sign gene for multiple tumours, and also be used as the target gene for the tumour gene therapy.
目的研究新型非病毒载体磷酸钙纳米颗粒的生物学特性，评估其在肿瘤基因治疗中应用的前景。
ObjectiveTo study the biological characteristics of calcium phosphate nanoparticles and evaluate the promising in cancer gene therapy.
腺病毒作为新兴的载体因其转染效率和表达效率高而日益受到重视，成为肿瘤基因治疗的主要载体之一。
As the newly emerging vector, recombinant adenovirus is being given more attention and has become the major vector of gene therapy because of its high rate of transfection and expression.
病毒载体的靶向性问题是肿瘤基因治疗中的重要研究热点，靶向病毒载体是提高肿瘤基因治疗安全性和有效性的重要途径。
Vector tropism is a research hot spot in cancer gene therapy, and targeted viral vectors play a key role in the enhancement of safety and efficiency in cancer gene therapy.
肿瘤基因治疗是继手术、放化疗等传统治疗方法之后出现的一种全新的肿瘤治疗方法，并在科研和临床方面取得可喜的进展。
The genetic therapy of tumor is a bran-new way of treatment after the traditional therapy of surgery, radiotherapy and chemotherapy, and it has made great progress in the research and clinical field.
然而，肿瘤基因治疗同样面临一个特殊问题即转基因特异性表达于肿瘤部位问题，靶向性基因转导依然是目前基因治疗的一大障碍。
However, gene therapy for cancer is also faced with a specificity problem: the specific targeting of transgene expression to the site of the tumour.
胞内抗体作为一种新的基因治疗工具，在肿瘤基因治疗、人艾滋病基因治疗的实验研究及潜在的临床治疗方面展示了广泛的应用前景。
As a new gene therapy tool, intrabody brings forth extensive application foreground in the aspects of tumor gene therapy and human HIV gene therapy's experimental study and potential clinical therapy.
设计合适的核酶分子能够阻断癌基因的异常表达，逆转肿瘤细胞MDR，促进肿瘤细胞凋亡，有望成为肿瘤基因治疗的有效手段之一。
With appropriate designing, it could block oncogene's expression, reverse MDR, and promote tumor cell apoptosis. All these properties make the Ribozymes as potentially useful regent for gene therapy.
重点介绍了各种胸苷激酶(tk)同工酶的差异及其与癌症和细胞周期的关系，并介绍了最近利用tk基因进行肿瘤基因治疗研究的进展。
This paper introduce the differences in thymidine kinase (tk) isoenzymes and the relation of them to cancer and cell cycle as well as the progress of gene-therapy of cancer based on tk gene.
背景与目的：肿瘤坏死因子相关凋亡诱导配体（tumornecrosisfactor-relatedapoptosisinducingligand，TRAIL）有广谱的抗瘤作用，且对正常组织细胞无毒性，因此有望应用于肿瘤基因治疗。
BACKGROUND & OBJECTIVE: Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) can induce apoptosis in various cancer cell lines with little toxicity toward normal cells.
大部分基因治疗的工作集中在肿瘤上。
大部分基因治疗的工作集中在肿瘤上。
基因治疗的目的在于降低癌症复发的危险性，在原肿瘤处或附近或身体的远处其他地方。
He said the hope is that the gene therapy will reduce the risk that cancer will recur at or near the site of the tumor as well as in distant points in the body.
由于肿瘤发生的复杂性及患者的异质性，往往要将基因治疗与其它疗法相结合才能收到满意的疗效。
Because of the complexity of tumors and heterogeneity of human, gene therapy is often needed to combined with other therapies to obtain good effect.
基因治疗已在治疗多种人类重大疾病如遗传病、肿瘤等方面显示出良好的应用前景，但也面临着巨大的挑战，主要是如何选择安全、高效、靶向的载体系统。
Gene therapy has shown great potentials in the treatment of a number of human key diseases, such as genetic diseases, cancer and so on, yet there are still some big challenges to face.
为今后临床应用分子生物学手段或基因治疗肿瘤提供资料。
Our research may be helpful to gene treatment of glioma by molecular biology methods.
卵巢癌是恶性度最高的妇科肿瘤之一，由于手术和化疗的不尽人意，基因治疗是当今肿瘤研究的热点。
Ovarian cancer is one of the most malignant tumors in women. Gene therapy is the hot spot in tumor research because of the low efficiency of the operation and chemical therapy.
通过对PTEN、EGFR、P 16蛋白的表达研究，为肿瘤的靶基因治疗策略提供了理论依据。
To study the expression of PTEN, EGFR and P16 protein will build up target gene therapy foundation of astrocytoma.
肿瘤靶向基因治疗的主要目的是用靶向性的载体将治疗基因靶向传递到肿瘤细胞。
A major goal of tumor-targeting gene therapy is to transfer genes efficiently to tumor cells by targeted vectors.
结论：IL - 2或TNF肝癌特异性原位基因治疗介导免疫抗肿瘤反应，但机理有所不同。
Conclusion: In situ hepatoma-specific gene therapy with IL-2 and TNF gene mediates anti-hepatoma immune response, but the mechanisms seem different.
概述了脱氧核酶的结构特点、修饰和设计策略、催化特点、在基因治疗中的优势及作为一种新型的基因治疗工具在肿瘤治疗中的应用。
This article introduced the DNAzyme in such spects as structures, modifications, designing strategies, catalytic traits, advantages as well as its application as a new tool of gene therapy of tumor.
此外，双歧杆菌专性厌氧的特性使其在肿瘤的基因治疗中起重要的作用。
Besides, bifidobacterium can produce a marked effect on cancer gene therapy because of its obligate anaerobic character.
本发明复合制剂和使用方法可用于指导和辅助眼病、遗传性疾病和肿瘤等的基因治疗。
The compound preparation and application method thereof can be used in instructing and assisting gene therapy for ophthalmopathy, genetic disease and tumor.
目的探讨共刺激分子B7 1 (CD80)在血液系统恶性肿瘤发病学及免疫基因治疗中的重要作用。
Objective to explore the significance of costimulatory molecule B7-1 (CD80) and MHC molecules in the pathogenesis of hematologic malignant tumors and in the immuno-genetic therapy.
将中医中药治疗肿瘤与基因治疗肿瘤的思路联系起来。
Associate the considerations on the treatment of tumor by Chinese medicine and those by gene therapy.
将中医中药治疗肿瘤与基因治疗肿瘤的思路联系起来。
Associate the considerations on the treatment of tumor by Chinese medicine and those by gene therapy.
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