结论:此两种载体为“正反馈”式放大肿瘤免疫原性提供一条新途径。
Conclusion: The constructed vectors can be a new route for enlarging tumor immunogenicity.
目的:提高肿瘤细胞的免疫原性。
根据诱导t淋巴细胞增殖能力、对肿瘤细胞的特异性识别及释放细胞因子能力评价多肽的免疫原性及免疫反应性。
The immunogenicity and immune reactivity of peptide were evaluated on the basis of t, cell proliferation assay, specific recognition of tumor cells and cytokines release.
但是,肿瘤的低免疫原性和机体对肿瘤的低免疫反应性,使得免疫治疗受到限制。
But the decreased immunogenicity and the body's low immune response to tumor restrict the use of the immunotherapy.
肿瘤细胞几乎100%地感染EBV,病毒蛋白有一定的免疫原性,是理想的肿瘤抗原。
The tumor cells almost infect the EBV 100%. There is some immunogenicity in the viral protein, which is the ideal tumor antigen.
研究表明,光动力学治疗可能通过杀死或诱导凋亡,改变了肿瘤细胞的生物学特性,提高了肿瘤细胞的免疫原性。
The study declares PDT change the biological character of tumor cells, enhances immunogenicity by inducing tumor cell apoptosis or killing tumor cell directly.
提示肿瘤细胞膜抗原及糖蛋白表达的改变可能是细胞因子基因转导影响肿瘤细胞免疫原性的重要结构基础。
The effect of various gene transduction on the expression of tumor cell MHC antigen and lectin receptors was investigated b…
提示肿瘤细胞膜抗原及糖蛋白表达的改变可能是细胞因子基因转导影响肿瘤细胞免疫原性的重要结构基础。
The effect of various gene transduction on the expression of tumor cell MHC antigen and lectin receptors was investigated b…
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