肾透明细胞癌高表达免疫抑制分子的机制需进一步研究。
The mechanisms of high expression of immunosuppressive molecules in the advanced stage ccRCCs require further investigation.
结论国人原发性散发性肾透明细胞癌中存在VHL基因的突变。
Conclusion The VHL gene may frequently mutate in Chinese patients with primary sporadic renal clear cell carcinoma.
目的研究肾透明细胞癌中趋化性细胞因子受体CX CR4的分布。
To explore distribution of chemokine receptor CXCR4 on clear cell renal carcinoma.
方法回顾性分析5例肾透明细胞癌转移瘤行手术治疗患者的临床资料。
Methods The clinical data of 5 patients with kidney carcinoma after metastasectomy were retrospectively analyzed.
观察CD 2ap在囊性肾透明细胞癌中的表达及其与临床病理特征的关系。
Observed the expression of CD2AP in multilocular cystic renal cell carcinoma and its relationship with clinic pathologic feature.
目的探讨国人原发性散发性肾透明细胞癌中VHL抑癌基因突变及其意义。
Objective To investigate the mutation of Von Hippel-Ldau(VHL)tumor suppressor gene in peatients with primary sporadic human renal cell carcinoma(RCC).
本实验将通过研究女性肾透明细胞癌及正常肾组织的X染色体失活类型判断肾透明细胞癌克隆起源。
To assess the clonal origin of renal clear cell carcinomas by the study of X-chromosome inactivation pattern in female clear cell renal carcinomas and normal renal tissues.
目的探讨CD 2相关蛋白(CD2AP)在囊性肾透明细胞癌中的表达及其与临床病理特征的关系。
Objective To explore expression of CD2-associated protein (CD2AP) in multilocular cystic renal cell carcinoma and its relationship with clinic pathologic feature.
方法对4例儿童肾透明细胞癌组织进行病理形态观察,并用图象分析仪对癌细胞DNA进行定量分析。
Methods The pathologic morphology of 4 cases of RCCC in children were observed. Using image analysis instruments the quantity of tumor cell DNA was measured.
结论:国人非遗传性肾透明细胞癌中存在VHL基因的突变,且与患者年龄,肿瘤分期、分级无相关性。
The mutations of VHL gene were irrespective of the age and pathological grade and stage of patients.
结论:肾透明细胞癌NOTCH1和JAG1表达均高于正常肾组织,且与肿瘤分级、分期及肿瘤大小有关。
Conclusions: The expression levels of NOTCH1 and JAG1 were higher in clear cell renal cell carcinoma than in normal kidney tissues and correlated with patients' clinical and pathological variables.
目的研究环氧化酶-2(COX-2)在人肾透明细胞癌组织中的表达,分析其表达水平与肿瘤分期的关系。
Objective To study the expression of cyclooxygenase-2 (COX-2) in renal clear cell carcinoma tissues and its relation with the clinical tumor stage.
其结果大多数癌除肝细胞肝癌、肾透明细胞癌外,大部分肿瘤细胞显示中等度到强阳性。在滑膜肉瘤、恶性间皮瘤及胸腺瘤上皮样成份弱阳性。
The majority of the carcinomas, except hepatocellular, adrenocortical clear cell ones are stained of strong or moderate intensity in the majority of tumor cells.
多房性肾细胞癌的囊内有透明细胞的聚集,其间有分隔。
Multilocular renal cell carcinoma has aggregates of clear cells within the septa dividing cystic Spaces.
结果76例患者均行经腰部斜切口根治性肾切除术,病理诊断均为透明细胞癌。
Results All the 76 cases underwent radical nephrectomy through oblique incision in the lumbus. The excised tumors were pathologically confirmed to be clear cell carcinoma.
需要进一步临床随访,来确定与传统透明细胞肾细胞癌相比这些肿瘤是否更为惰性。
Further clinical follow-up is needed to determine whether these tumors are more indolent compared with the conventional clear cell renal cell carcinoma.
螺旋CT鉴别透明细胞癌与非透明细胞癌的准确性在皮髓质期、肾实质期、排泄期分别为93.5%、86.9%、81.5%。
Accuracy of ct for differentiating clear cell and non-clear cell carcinoma in three enhanced phases was 93.5%, 86.9% and 81.5%, respectively.
螺旋CT鉴别透明细胞癌与非透明细胞癌的准确性在皮髓质期、肾实质期、排泄期分别为93.5%、86.9%、81.5%。
Accuracy of ct for differentiating clear cell and non-clear cell carcinoma in three enhanced phases was 93.5%, 86.9% and 81.5%, respectively.
应用推荐