慢性接触镉主要引起肾小管损伤，表现为蛋白尿、糖尿和氨基酸尿。
Chronic exposure to Cd mainly causes the renal proximal tubule damage, which represents that the excretion of proteinuria, glucosuria and aminoaciduria.
结论本方法灵敏度高、且专一性较好，为研究肾小管损伤奠定了基础。
Conclusion This method has higher sensitivity and better specificity, and has established the foundation for studying renal tubule lesion.
急性肾小管损伤(ati)经常发生在移植肾，尤其是肾移植后早期。
Acute tubular injury (ati) is commonly observed in renal allografts, especially early after transplantation.
同时测定肾小管损伤组儿童尿NAG酶的水平，明显高于肾病组与对照组；
Meanwhile, the urine NAG enzyme in children with renal tubule lesion was significantly higher than that in the nephrosis group and the control.
慢性接触镉主要引起肾小管损伤，表现为蛋白尿、糖尿、氨基酸尿、酶尿及尿镉排出量明显增加等。
Chronic exposure to Cd mainly causes the renal proximal tubule damage, which represents that the excretion of proteinuria, glucosuria, aminoaciduria, enzymaticuria and urinary cadmium increase.
这项研究探讨肾小管损伤的生物标记是否可在实验设计中检测出亚临床小管损伤从而考虑行无创性的筛查操作。
This study investigated whether urinary tubular injury biomarkers can detect subclinical tubulitis found in protocol biopsies allowing for a noninvasive screening procedure.
目的建立尿中性肽内切酶(NEP)检测的ELISA法，明确用ELISA法检测尿nep在诊断肾小管损伤中的意义。
Objective to set up an ELISA method to measure urinary neutral endopeptidase (NEP) and determine its clinical meaning in diagnosing renal tubular injury.
肾囊肿的发生原因尚不完全清楚，可能与先天性肾小球、肾小管结构异常和后天性损伤感染有关。
The reasons of Renal Cyst occur still unconfirmed, may occur from congenital glomerular, renal tubular structure anomalies and postnatal damage infection.
结论TIMP - 1过表达可通过增强炎症加重肾小管间质损伤。
Conclusions Overexpression of TIMP-1 exacerbates renal tubulointerstitial injury by enhancing inflammation.
这些结果说明，细胞外高钙能够直接损害肾小管上皮细胞，但不是通过损伤细胞膜的方式来实现的。
It is concluded that high extracellular calcium can injure renal tubular cells, but not by the way of destroying the plasma membrane integrity.
引起肾小管间质病变的原因比较复杂，其中蛋白尿的肾损伤作用已为大量临床和实验研究所证实。
The causes for tubulointerstitial changes remain rather complex and the role of proteinuria in damaging nephridial tissue has been demonstrated by large number of clinical and experimental studies.
肾间质纤维化；肾小管上皮细胞；线粒体氧化损伤；肾小管功能。
Renal interstitial fibrosis; Renal tubular epithelial cell; Mitochondria oxidative damage; Renal tubular function.
另外，在增生性肾小球肾炎中损伤的肾小球和肾小管dna断裂显著相关。
Furthermore, glomerular damaged showed a significant correlation with tubular DNA damage in proliferative gn.
结果：肾小球系膜区FN与系膜细胞增生、肾小球损伤程度及肾小管间质损伤程度均呈正相关。
Results Positive correlations were found between the degree of FN in glomerular mesangium or basement membranes and glomerular lesion grading or tubulointerstitial lesion grading.
病理观察到肾损伤的部位主要是皮髓交界处的近曲肾小管。
The main renal injury location was in proximal convoluted tubule.
单变量分析表明，血清肌酐水平、肾小球和肾小管间质损伤的严重程度都与高尿酸血症显著相关。
Univariate analysis showed that the level of serum creatinine and the severity of glomerular and tubular interstitial injury were significantly related to hyperuricemia.
结论依达拉奉可以保护心肺复苏后大鼠肾功能，其机制可能与减轻氧自由基损伤，抑制肾小管上皮细胞的凋亡有关。
Edaravone can protect renal function in rats after cardiopulmonary resuscitation, partly through abatement of oxyradical lesion and inhibition of cell apoptosis.
结论：急性缺血性肾损伤时，中药粉防己碱能够调节肾小管上皮细胞的凋亡水平，以减轻肾组织的损伤。
Conclusion: Tetrandrine can adjust the level of apoptosis in renal tubular epithelial and alleviate renal tissular injury.
结论：急性缺血性肾损伤时，中药粉防己碱能够调节肾小管上皮细胞的凋亡水平，以减轻肾组织的损伤。
Conclusion: Tetrandrine can adjust the level of apoptosis in renal tubular epithelial and alleviate renal tissular injury.
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