肾血宁胶囊能抑制肾小球系膜细胞的增殖，并通过下调FN在肾内的表达，抑制肾小球细胞外基质的积聚；
Shen-Xue-Ning capsule can inhibit mesentery cell hyperplasia and extracellular matrix collection of glomerular by regulating FN in kidney;
图像分析显示：贞清方高、低剂量组肾小球细胞外基质相对面积较模型组降低（P<0.01，P<0.05）。
Microimage analysis showed that the level of glomerular extracellular matrix in high and lowdosage groups were less than that in untreated group(P<0.01, P<0.05).
目的观察缓激肽（BK）对高糖浓度下肾小球系膜细胞增殖和细胞外基质分泌的影响。
Objective To observe the effect of bradykinin(BK) on kidney mesangial cell multiplication and extracellular matrix secretion under high glucose environment.
减轻肾小球硬化细胞外基质的积聚。
Cordycepssinensis can alleviate the accumulation of extracellular matrix.
目的探讨“延肾胶囊”对残肾肾小球系膜细胞凋亡及其细胞外基质代谢的影响。
Objective To elucidate the effect of Yan-Shen Capsule on glomerular mesangial cell apoptosis and extracellular matrix metabolism of remnant kidney.
肾小球系膜细胞(GMC)的增殖通过影响细胞外基质(ecm)的分泌和对肾小球毛细血管的机械损伤而在肾小球硬化过程中发挥着重要作用。
BackgroundThe GMC proliferation plays an important role in glomerular sclerosis by influencing the ECMs secretion and mechanical injury on the glomerular capillaries.
GMC增殖可引起细胞外基质（ECM）过量生成和聚集，并最终导致肾小球硬化（GS）、肾脏纤维化及终末期肾功能衰竭。
The proliferation of GMC can induce extracellular matrix(ECM) expansion, which can lead to glomerulosclerosis(GS), renal fibrosis and even end stage renal failure in the final.
GMC增殖可引起细胞外基质（ECM）过量生成和聚集，并最终导致肾小球硬化（GS）、肾脏纤维化及终末期肾功能衰竭。
The proliferation of GMC can induce extracellular matrix(ECM) expansion, which can lead to glomerulosclerosis(GS), renal fibrosis and even end stage renal failure in the final.
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