全文综述检测肺癌相关基因用于肺癌早期诊断的研究进展。
The progress on lung cancer related genes for the diagnosis of early stage lung cancer is reviewed in this paper.
目的:探讨辐射诱发人支气管上皮细胞(BEP2D)转化过程中肺癌相关基因的表达。
Objective:This study was designed to profile the expression patterns of 60 lung cancer related genes in human bronchial epithelial transformation cell model (BEP2D) induced by radiation.
目的克隆人肺癌相关抗原的基因。
Objective To clone the gene of human lung cancer associated antigen.
目的探讨人肺癌细胞株对化疗药物的敏感性与多药耐药相关基因和凋亡调控基因表达的关系。
Objective To explore the relationship of chemotherapy sensitivity and expression of multidrug resistance genes and apoptosis regulation genes in human lung cancer cell lines.
目的发现与肺癌转移相关的基因。
结论FHIT基因可能参与肿瘤细胞增殖的调控,FHIT基因表达下降可能与肺癌的发生密切相关。
Conclusion FHIT gene may play a role in the regulation of cell proliferation of lung cancer, and the reduction in FHIT expression may be related to the pathogenesis of lung cancer.
发现与肺癌和其他癌症相关的常见基因变异。
Several common genetic variants linked to the risk of lung and other cancers.
结论:RRAGA基因与肺癌无相关性,中国人RRAGA基因的SNP与外国人的有很大差别。
Conclusion: the RRAGA gene was irrelevant for lung cancer, and the SNP of RRAGA gene was distinct between Chinese and foreigners.
肺癌组织中FHIT基因表达水平降低与肺癌组织学类型、细胞分化程度,患者PTNM分期、淋巴结转移程度存在相关性(P< 0 .0 5) ;
The expression level of FHIT gene was closely related to histological classification, cancer cell differentiation, P TNM stages and lymph node involvement in lung cancer patients (P<0.05).
鉴定和研究相关癌基因和抑癌基因的功能有望为肺癌防治提供新的靶标,因而一直是肺癌研究领域内的热点。
Identification and research on the oncogenes and the tumor suppressor genes will provide new targets of prevention and treatment to lung cancer.
鉴定和研究相关癌基因和抑癌基因的功能有望为肺癌防治提供新的靶标,因而一直是肺癌研究领域内的热点。
Identification and research on the oncogenes and the tumor suppressor genes will provide new targets of prevention and treatment to lung cancer.
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