目的研究丙烯腈(acn)对小鼠肺成纤维细胞增殖分化的影响。
Objective To approach the effect of acrylonitrile (ACN) on the proliferation and differentiation of the lung fibroblasts of mice.
目的探讨青石棉致人胚肺成纤维细胞(HEPF)增殖的细胞周期变化的机制。
Objective To explore the mechanism of cell proliferation cycle change of human embryonic pulmonary fibroblasts (HEPF) induced by crocidolite.
应用氯化镉致人胚肺成纤维细胞恶性转化实验、染色体分析、流式细胞术对氯化镉的致癌机理进行研究。
The mechanism of carcinogenesis induced by CdCl 2 was studied through experiments of the malignant transformation of human embryo lung fibroblast in vitro, chromosome analysis and flow cytometry.
目的：研究依他酸（EA）和卡西霉素（Cal）对人胚肺成纤维细胞脱氧核糖核酸和胶原合成的影响。
AIM: To study the effects of egtazic acid (EA) and calcimycin (Cal) on the synthesis of DNA and collagen in cultured human lung fibroblasts (HLF).
与矽肺的发病相似，特发性肺纤维化(IPF)也是以肺成纤维细胞大量增殖为主要特征的肺纤维化疾病。
Similar to the silicosis, idiopathic pulmonary fibrosis (IPF), which is another lung interstitial disease, is characterized by lung fibrosis.
肺成纤维细胞除与普通的成纤维细胞类似外，它们还有自身的一些特点，如具有较长的分支过程和缝隙接合。
They resemble ordinary fibroblasts but have some distinguishing features, for example, they have long branching processes and gap junctions.
方法从培养的人胚肺成纤维细胞(WI- 38)中提取总rna，经rt -PCR获得人破骨细胞抑制因子基因。
METHODS Total RNA was extracted from human embryonic lung fibroblast cells (WI 38) and the whole length gene of human OPG was obtained by RT PCR.
同时以端粒酶阳性的永生化人胚肾成纤维细胞HEK293作为阳性对照，以端粒酶阴性的人胚肺成纤维细胞HELF作为阴性对照。
Immortalized human embryonic kidney cell line HEK293 and the human embryonic lung fibroblasts HELF were used as positive control and negative control, respectively.
目的检测阿霉素、重铬酸钾和过氧化氢所致中国仓鼠肺成纤维细胞（CHL）DNA的损伤效应及酪醇对真核细胞DNA氧化损伤的保护作用。
Objective To detect the DNA strand breaks induced by adriamycin, potassium chromate or hydrogen peroxide and to study the effect ofp tyrosol on DNA oxidative damage in CHL cells.
研究发现，SO_2及其衍生物可引起人外周血淋巴细胞、小鼠骨髓细胞、中国仓鼠肺成纤维细胞等哺乳动物细胞的染色体畸变、姊妹染色单体交换及微核的形成。
Several studies have shown that SO2 and its derivatives could induce chromosomal aberrations, sister chromatid exchanges and micronuclei in human blood lymphocyte, bone marrow cell in mice and CHL.
结果表明，体外培养人胚肺二倍体成纤维细胞成活至52代，而含0。2%黄芪制取液的培养基使细胞成活至77代。
The results showed that heldf cultured in vitro lived up to52generations while the culture medium containing0.2% amb extract made the cells live up to77genera-tions.
结果表明，体外培养人胚肺二倍体成纤维细胞成活至52代，而含0.2%黄芪制取液的培养基使细胞成活至77代。
The results showed that HELDF cultured in vitro lived up to 52 generations while the culture medium containing 0.2% AMB extract made the cells live up to 77 generations.
目的观察衰老的人胚肺二倍体成纤维细胞(2bs)对烷化剂甲磺酸甲酯(MMS)诱导的DNA损伤的应答。
Objective to explore the cellular response of human senescent diploid fibroblasts (2bs) to the DNA damage caused by methyl methanesulfonate (MMS).
而消化的人胚肺组织中细胞形态不一，经继续培养4～5代后，培养物完全由成纤维细胞构成。
The shapes of human embryonic lung fibroblasts which were isolated by enzyme digestion were differ, and the culture was all composed of fibroblasts after subculturing for 4-5 generations.
光镜观察所见，给予PNS治疗7天后，各给药组肺间质及肺泡腔中炎性细胞渗出及成纤维细胞增殖较模型组有不同程度的减轻（P<0.05，P<0.01）；
PNS can significantly reduce inflammatory cells exudation and fibroblast proliferation in pulmonary interstitium and alveolar spaces on the 7th day after drugs administration(P<0.05, P<0.01).
光镜观察所见，给予PNS治疗7天后，各给药组肺间质及肺泡腔中炎性细胞渗出及成纤维细胞增殖较模型组有不同程度的减轻（P<0.05，P<0.01）；
PNS can significantly reduce inflammatory cells exudation and fibroblast proliferation in pulmonary interstitium and alveolar spaces on the 7th day after drugs administration(P<0.05, P<0.01).
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