目的:探讨缺氧对大鼠肺动脉平滑肌细胞的作用机制。
To investigate the effect of hypoxia on rat pulmonary smooth muscle cell (PSMC).
目的:探讨JWA核酶基因转染对肺动脉平滑肌细胞表型及迁移的影响。
AIM: To investigate the effects of transfected JWA ribozyme gene on phenotype and migration of human pulmonary artery smooth muscle cells (PASMCs).
肺动脉高压大鼠肺动脉平滑肌细胞1,4,5 -三磷酸肌醇受体表达的变化。
Changes in 1, 4, 5-trisphosphate receptor expression in pulmonary artery smooth muscle cells of pulmonary hypertensive rats.
肺动脉平滑肌细胞膜亦有NHE-1表达,在低氧条件下表达明显增高,其特异性抑制剂可明显抑制肺动脉平滑肌细胞增殖。
The expression of NHE-1 in the membrane of PASMCs is elevated remarkably under hypoxia condition and the NHE-1 specific inhibitors can suppress the PASMCs proliferation.
氨溴索干预组的肺动脉平滑肌细胞和细胞外基质的病变明显轻于低氧组,管壁面积占总面积的百分比和管壁厚度占外径的百分比明显低于低氧组(P <0 0 1)。
PAPM in AP group is significantly lower than that of CIH group ( P< 0.01); The damage of pulmonary artery smooth muscle cells and extra cell matrix of AP group is much slighter than that of CIH group.
用胰蛋白酶和胶原酶消化法和组织贴块法培养猪肺动脉干内皮细胞和平滑肌细胞。方法简便易行,成功率高。
Endothelial cells and smooth muscle cells of porcine pulmonary trunk were cultured by enzyme-dispersed and substrate-attached explant methods.
用胰蛋白酶和胶原酶消化法和组织贴块法培养猪肺动脉干内皮细胞和平滑肌细胞。方法简便易行,成功率高。
Endothelial cells and smooth muscle cells of porcine pulmonary trunk were cultured by enzyme-dispersed and substrate-attached explant methods.
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