肠道转运体、肝脏药物代谢酶及肾脏在药物adme过程中发挥着重要作用。
Intestinal drug transporters, hepatic drug metabolic enzymes and the kidney play a very important role in the process of ADME.
您能谈一下治疗代谢综合征的药物会对肝脏产生怎样的损伤吗?
肝脏代谢药物的能力和肾脏排泄药物的能力随着年龄的增长而下降。
The abilities of the liver to metabolize drugs and of the kidney to excrete drug metabolites decline with the aging process.
CYP3A29是猪肝脏最重要的药物代谢关键酶。
CYP3A29 is the most important key enzyme for drug metabolism in pig's liver.
肝脏是大部分药物转化代谢的场所,一些药物在肝脏代谢时,其本身或其代谢产物可对肝细胞产生直接或间接的毒性损伤。
The liver is the majority of medicines transformation metabolism place, when liver metabolism, some medicines itself and its metabolite may have direct or the indirect toxic damage to the liver cell.
这是因为这些药物需要肝脏代谢的时候,肝脏还在拼命消除前晚喝的酒。这就是为什么有人反对使用止痛药的原因。
This is because they give the liver work to do when it is already stretched trying to deal with all the alcohol from the previous evening, so the argument goes.
这组作者报告说,这些肝脏有效地移植了过去,而且这些小鼠在数周时间里展现出了人类肝脏的功能,包括人类蛋白质的合成以及人类药物代谢。
Mice transplanted with HEALs exhibit humanized liver functions persistent for weeks, including synthesis of human proteins, human drug metabolism, drug–drug interaction, and drug-induced liver injury.
虽然老鼠的肝部基因恢复活力不会逆 转它们在其他方面的老化,但是却有助于这些老鼠的肝脏对药物的新陈代谢和清除毒素。
The genetic rejuvenation won't reverse other damage caused by time for the mouse, but could help its liver metabolize drugs or get rid of toxins.
肝脏微粒体细胞色素P - 450依赖性药物代谢酶(简称MCP - 450)系统和免疫系统是重要的防御体系。
While the microsome cytochrome P450dependent drug metabolic enzyme (MCP450) in liver is organism's defense system to lipid foreign body.
肝脏微粒体细胞色素P - 450依赖性药物代谢酶(简称MCP - 450)系统和免疫系统是重要的防御体系。
While the microsome cytochrome P450dependent drug metabolic enzyme (MCP450) in liver is organism's defense system to lipid foreign body.
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