目的应用噬菌体表面展示技术寻找原因不明性肝炎血清蛋白成分在肝细胞表面的结合蛋白,探讨原因不明性肝炎发病机制。
To search for liver surface binding protein of serum protein composition in idiopathic hepatitis by phage display technique, and investigate the pathogenesis of idiopathic hepatitis.
研究了一些胰岛素B链羧端肽段改变了的类似物与肝细胞及脂肪细胞的受体蛋白结合性质。
The receptor-binding properties of insulin and its analogs with modified C-terminal peptide sequence of the B-chain have been studied in liver cells and fat cells.
pcsk9结合低密度脂蛋白受体表面上的肝细胞和原因,这些受体打破。
PCSK9 binds to LDL receptors on the surface of liver cells and causes those receptors to break down.
本发明申请提供一种结合肝细胞生长因子(HGF)(特别是人hgf)并中和其活性的结合蛋白质家族。
The present invention provides a family of binding proteins that bind and neutralize the activity of hepatocyte growth factor (HGF), in particular human HGF.
表3.对照组及高胆固醇组家兔肝细胞膜高密度脂蛋白受体的最大结合值和解离常数值。
Table 3. Bmax and Kd of HDLR in hepatic plasma membranes of rabbits in control and high cholesterol groups.
应用受体的放射配基结合分析法测定出甜菜碱对大鼠肝细胞膜表皮生长因子受体(EGF)及其酪氨酸蛋白激酶(TPK)有显著的结合抑制作用。
Using radioligand of binding assay of receptors determinates that betaine can inhibit the binding of EGF receptor with EGF and affect the TPK activity conspicuously.
应用受体的放射配基结合分析法测定出甜菜碱对大鼠肝细胞膜表皮生长因子受体(EGF)及其酪氨酸蛋白激酶(TPK)有显著的结合抑制作用。
Using radioligand of binding assay of receptors determinates that betaine can inhibit the binding of EGF receptor with EGF and affect the TPK activity conspicuously.
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