通过递增乙醇浓度，日3次胃内灌注乙醇来复制酒精性肝纤维化动物模型。
The rat model of alcoholic liver fibrosis was induced by intragastric infusion of increasing concentration of ethanol 3 times per day.
目的通过大鼠肝纤维化动物模型，研究门冬氨酸鸟氨酸防止肝纤维化的作用。
Objective To study the role of ornithine aspartate on preventing of liver fibrosis through the rat liver fibrotic model.
目的：探讨高脂饮食与酒精对肝纤维化的形成机制，寻求新的肝纤维化动物模型。
Objective: To establish new animal model of hepatic fibrosis with rats and to study the causative mechanism of hepatic fibrosis induced by high fat diet and alcohol.
《国际肝病》：几种临床前期的试验研究表明，进行试验的抗肝纤维化药物对于肝纤维化动物模型并不是很有效。
Hepatology Digest: Several preclinical studies showed that experimental anti-fibrotic drugs are not effective in animal models with liver fibrosis.
方法采用以人血白蛋白攻击方法制备肝纤维化动物模型，放免法测定血TNF ，免疫组化法观察肝内层粘蛋白改变。
Methods The rat models of hepatic fibrosis were established by human serum albumin(HSA) injection. Serum TNF was detected by RIA method and laminin in the liver was studied by immunohistochemistry.
方法采用以人血白蛋白攻击方法制备肝纤维化动物模型，放免法测定血TNF ，免疫组化法观察肝内层粘蛋白改变。
Methods The rat models of hepatic fibrosis were established by human serum albumin(HSA) injection. Serum TNF was detected by RIA method and laminin in the liver was studied by immunohistochemistry.
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