聚酮化合物是一类重要的具有生物活性的次级代谢物。
Polyketides are an extremely important class of bioactive secondary metabolites.
利用异源宿主合成聚酮化合物要比使用天然生产菌有很多优点。
The production of polyketides in heterologous hosts offers many advantages over the use of natural producers.
最突出的例子就是一种最近发现的天然聚酮化合物——discodermalide，它在海绵中提炼，但数量极少。
A prime example is discodermalide, produced naturally by a marine sponge, but in very small quantities.
描述了包括总共具有15个组件的聚酮化合物合酶、具有1个组件的非核糖体肽合成酶和细胞色素P 450羟化酶组成的聚酮化合物合酶复合物。
A polyketide synthase complex composed of polyketide synthase with 15 total modules, a non-ribosomal peptide synthetase with I module, and a cytochrome P450 hydroxylase is described.
描述了包括总共具有15个组件的聚酮化合物合酶、具有1个组件的非核糖体肽合成酶和细胞色素P 450羟化酶组成的聚酮化合物合酶复合物。
A polyketide synthase complex composed of polyketide synthase with 15 total modules, a non-ribosomal peptide synthetase with I module, and a cytochrome P450 hydroxylase is described.
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