多药耐药相关基因与蛋白的检测。
Detection of multidrug resistance-related genes and proteins.
本文通过实验方法研究设计和临床应用，探讨肿瘤多药耐药基因（MDR-1）的异常表达检测方法及其临床意义。
Through experimental method design and clinical application, this paper investigated the detecting method and clinical significance of multi-drug resistance gene (MDR-1) expression.
目的探讨快速检测结核分枝杆菌异烟肼（INH）耐药基因型的分子药敏方法。
Objective One of the main mechanisms of isoniazid (INH) resistance is catalase peroxidase katG gene mutation of Mycobacterium tuberculosis .
方法应用rtP CR检测abc家族基因的转录表达，MTT法检测耐药性改变。
Methods Expression of ABC family genes was examined by RT PCR, and cell growth by MTT test.
目的：检测麻风菌的氨苯砜、利福平耐药基因，以了解复发与耐药的关系。
Objective: To detect resistant stains of Mycobacterium leprae to dapsone (DDS) and rifampicin (RFP) and to understand the relationship between relapse and drug resistance.
目的利用基因芯片技术进行常见革兰阳性细菌的细菌鉴定和耐药性检测。
Objective To study the clinical application of DNA chip for common Gram-positive bacteria identification and drug resistance detection.
结果与临床常规方法相比，耐药检测基因芯片鉴定指标的灵敏度均>96%，特异度均>98%；
Results The sensitivity of all identification indexes of DNA chip were higher than 96%, and all of their specificity were higher than 98%.
目的通过检测儿童急性白血病多药耐药基因及细胞凋亡调控基因表达水平的改变，分析不同类型白血病的主要耐药机制。
Objective To study the drug resistance in different types of acute leukemia in children, the expression of multidrug resistance gene and apoptosis-related genes were analyzed.
可简便、快速地检测细菌、真菌、衣原体和支原体的耐药基因，尤其联合检验对临床早期诊断、治疗及鉴定耐药菌株及亚型具有一定价值。
Particularly, combined detection of drug resistance may help obtain early diagnosis and more directed antibiotic therapy and strain identification of resistant organisms.
目的：探讨结核分支杆菌对异烟肼、利福平耐药的分子机制，建立快速检测耐药分支杆菌基因型的分子生物学方法。
Objective: To study on the molecular mechanisms of isoniazid and rifampin resistant tuberculosis and explore its rapid detection methods.
目的研究基因芯片在检测结核分枝杆菌利福平和异烟肼耐药性中的应用。
Objective To study the application of gene chip in detecting Mycobacterium tuberculosis resistant to rifampin (RFP) and isoniazid (INH).
目的：建立人舌鳞状细胞癌耐放疗细胞系并检测多药耐药基因和蛋白的表达。
Objective: To establish a radiation-resistant human tongue squamous carcinoma cell line and to detect the expression of multidrug-resistant gene( MDR1) and protein (P-gp).
本文就HIV-1表型耐药定义、检测方法、存在优缺点及其与基因型耐药检测结果一致性等进行综述。
Definition, testing, advantage and disadvantage of phenotypic resistance assay of HIV-1 and its concordance with genotypic resistance assay were summarized in this paper.
耐药基因的检测多以聚合酶链反应为基础，可以直接检测标本，从而快速、早期为临床选择抗菌药物提供依据。
Most genetic methods are based on PCR, and can be used directly in clinical specimens to guide therapy early and rapidly.
（in Chinese）汪永禄，王多春，张萍，等。临床患者标本金黄色葡萄球菌肠毒素基因及耐药性的检测分析 [J]。公共卫生与预防医学，2013，24（2）：18-22。
Wang YL, Wang DC, Zhang P, et al. Enterotoxin genes of Staphylococcus aureus of clinical specimens and drug resistance [J]. Journal of Public Health and Preventive Medicine, 2013,24(2):18-22.
耐药基因的检测，对临床用药有指导意义，有助于克服耐药，提高化疗疗效。
Measurement of the expression of MDRl and MRP genes in patients' tumor might help in selecting sensitive drugs to overcome drug resistance, therefore improve treating effects.
耐药基因的检测，对临床用药有指导意义，有助于克服耐药，提高化疗疗效。
Measurement of the expression of MDRl and MRP genes in patients' tumor might help in selecting sensitive drugs to overcome drug resistance, therefore improve treating effects.
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