结果:优化所得处方为微晶纤维素40%,羧甲基淀粉钠10%,糊精约15%。
Result: the optimized formulation contained 40% microcrystalline cellulose, 10% sodium carboxymethyl starch and 15% dextrin.
选用两种辅料,进口羧甲基淀粉钠和羟丙纤维素进行对比实验,确定最后辅料的使用。
Choose two kinds of supplementary materials, imported Carboxymethylstach Sodium and Hyprolose, to have the contrastive experiments and make sure the use of final suppl.
方法:考察糊精、羧甲基淀粉钠、微晶纤维素和低取代羟丙基纤维素对银黄酮片的质量影响。
METHODS: the effects of dextrin, CMS-Na, microcrystalline cellulose and L-HPC on the quality of Ginkgo flavone tablets were studied.
方法考察糊精、微晶纤维素、羧甲基淀粉钠和低取代羟丙基纤维素对扁蓄总黄酮片的质量影响。
Medthods The effects of dextrin, microcrystalline cellulose, CMS-Na and L-HPC on the quality of the total Flavone of Polygonum Aviculare Tablets were studied.
结果:填充剂以微晶纤微素、淀粉,崩解剂以羧甲基淀粉钠效果最佳,各项指标均符合中国药典。
Results: Microcrystalline cellulose and Starch are the best Filler, Sodium carboxymethyl starch is the best Disinteg-rant, and all the indicators are accorded with Chinese Pharmacopoeia.
探讨了聚乙烯吡咯烷酮浓度,羧甲基淀粉钠用量对法莫替丁分散片崩解的影响及不同介质对其溶出的影响。
Famotidine dispersible tablets were prepared. The influence of PVP concentration, sodium starch glycolate quantity and different medium on disintegration and dissolution rate is discussed.
结果:优选的最佳处方为微晶纤维素20%、交联聚乙烯吡咯烷酮6%、羧甲基淀粉钠5.5%和聚乙烯吡咯烷酮8%。
RESULTS:The optimized formulation was composed of microcrystalline cellulose 20%, cross-link polyvinyl pyrrolidone 6%, sodium carboxymethyl starch 5.5% and polyvinyl pyrrolidone 8%.
羧甲基淀粉钠(CMS)作为一种重要的化工助剂以其独特的性能和较高的经济效益在工业生产的各个领域有着广泛的应用。
Carboxyl methyl starch sodium (CMS) is extensive applied in many fields of industrial production with its unique performance and hig her economic benefits as a kind of important chemical auxiliary.
方法将羧甲基淀粉钠、微晶纤微素按一定比例混合,作为片剂基本处方,以分散片的外观、崩解时限、体外溶出度及混悬性为指标进行处方筛选。
METHOD s Mixing the CMSNa and MCC in certain proportion as the basic formulation of the tablets, the appearance, disintegration, dissolution and the suspensibility were investigated.
方法将羧甲基淀粉钠、微晶纤微素按一定比例混合,作为片剂基本处方,以分散片的外观、崩解时限、体外溶出度及混悬性为指标进行处方筛选。
METHOD s Mixing the CMSNa and MCC in certain proportion as the basic formulation of the tablets, the appearance, disintegration, dissolution and the suspensibility were investigated.
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