目的探讨EB病毒LMP1羧基端胞浆区与端粒酶活化的关系。
Objective To study the relationship between carboxyl terminus region of EBV LMP1 and telomerase activation.
单克隆抗体由合成肽段免疫动物产生，该肽段与人p 21蛋白的羧基端一致。
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human p21 protein.
单克隆抗体由合成肽段免疫动物产生，该肽段与人cdc45蛋白的羧基端一致。
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human cdc45 protein.
单克隆抗体由合成肽段免疫动物产生，该肽段与人merit40蛋白的羧基端一致。
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human MERIT40 protein.
该单克隆抗体经由合成的围绕人RBX1蛋白近羧基端的氨基酸肽段免疫动物而生产的。
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues near the carboxy terminus of human RBX1 protein.
结论EB病毒LMP1可活化端粒酶活性，这一功能与LMP1羧基端胞浆区，特别是其功能域ctar1和CTAR2密切相关。
Conclusion EBV LMP1 is able to activate telomerase and this function is related to the carboxyl terminus region of LMP1, specially CTAR1 domain and CTAR2 domain.
结论EB病毒LMP1可活化端粒酶活性，这一功能与LMP1羧基端胞浆区，特别是其功能域ctar1和CTAR2密切相关。
Conclusion EBV LMP1 is able to activate telomerase and this function is related to the carboxyl terminus region of LMP1, specially CTAR1 domain and CTAR2 domain.
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