目的探讨羟基喜树碱对肠癌细胞的体外作用。
Objective: to explore the effect of hydroxy camptothecin on colorectal carcinoma cells in vitro.
目的考查国内不同企业羟基喜树碱制剂的产品质量。
OBJECTIVE To investigate the quality of hydroxycamptothecine preparations manufactured by different companies.
目的观察羟基喜树碱对晚期胃肠道恶性肿瘤治疗效果。
Objective To observe the clinical effect of HCP t treatment on advanced gastroenteric tract tumors.
各处理对喜树幼苗内10 -羟基喜树碱含量的影响无规律可循。
No available rules can explain changes of 10-oh camptothecin content under all treatments.
目的：研究10 -羟基喜树碱(HCPT)的内酯环形式与抗癌活性之间的关系。
AIM: to study the relationship between the lactone forms of 10-hydroxycamptothecin (HCPT) and their antitumor activities.
目的：探讨人胃癌耐羟基喜树碱细胞株即SGC-7901/HCPT的耐药机制。
Objective:To investigate drug-resistance mechanism of the camptothecin(HCPT)-resistant stomach cancer cell line SGC-7901/HCPT.
目的研究10 羟基喜树碱（HCAM ）抗人肺癌细胞增殖、侵袭和诱导凋亡的作用。
Objective To study the effects of 10-hydroxycamptothecin (HCAM) on the inhibition of proliferation, anti-invasion and induction of apoptosis in highly metastasis lung cancer cells (PGCL3).
目的：制备10 -羟基喜树碱的半固体脂质纳米粒(HCPT -SSLN)并考察其稳定性。
Objective: to prepare 10-hydroxycamptothecin-semisolid lipid nanoparticles (HCPT-SSLN) and investigate its stability.
目的研究草酸铂动脉介入联合羟基喜树碱(拓喜)腹腔灌注治疗直肠癌术后复发的近期疗效和毒副反应。
Objective: to investigate the efficacy and safety of Oxaliplatin intra-arterial infusion combined with Hydroxycampyothecin peritoneal infusion for treatment of relapse rectal cancer.
目的：观察低剂量羟基喜树碱(HCPT)联合低剂量flp方案治疗晚期消化系肿瘤的疗效和毒副作用。
Objective: to observe the response and toxicity of combination with low-dose HCPT and low-dose FLP in patients with advanced digestive carcinoma.
结论拓喜(羟基喜树碱)除了对小鼠艾氏腹水癌移植瘤抑制作用有明显的时辰差异外，对WBC的影响也有时辰的变化。
Conclusion the effect and WBC change of hydroxy camptothecin on chronotherapy in EAC mice had chrono-effect and changes.
结论喜树碱A环的9，10位增加一个“1，4 氧嗪2 酮”六元环后，其抗肿瘤活性要比喜树碱或10 羟基喜树碱的活性降低。
Conclusion The modification of a 1,4-oxazine-2-one ring fused with positions 9 and 10 of A-ring will reduce the antitumor activity of camptothecins.
其中，10羟基喜树碱、拓普替康、 伊立替康以及9氨基、9硝基喜树碱、7乙基10 羟基喜树碱等在临床显示了广泛的抗癌活性。
Among them, 10 hydroxycamptoyhecin, topotecan, camptothecin 11, 9 amino campothecin, 9 nitro campothecin and 7 ethyl 10 hydroxycamptoyhecin showed a great antitumor activity in wide verities of range.
目的：通过去氢骆驼蓬碱 （HM）微球与羟基喜树碱 （HCPT）注射液对大鼠正常肝细胞 （BRL ）的毒性作用的比较研究 ，为HM的临床应用提供佐证。
Objective: In order to offer evidence for the clinical application of HM(harmine), toxicity of HM and HCPT(hydroxycamptothecin) against the rat normal liver cell (BRL) was compared.
目的：通过去氢骆驼蓬碱 （HM）微球与羟基喜树碱 （HCPT）注射液对大鼠正常肝细胞 （BRL ）的毒性作用的比较研究 ，为HM的临床应用提供佐证。
Objective: In order to offer evidence for the clinical application of HM(harmine), toxicity of HM and HCPT(hydroxycamptothecin) against the rat normal liver cell (BRL) was compared.
应用推荐