目的：研究肿瘤细胞在缺氧及放射情况下细胞周期的改变及细胞存活的情况。
OBJECTIVE: To research the cell cycle change and cell surviving of the tumor cell undergone hypoxic and radiated condition.
结论肝动脉阻断后缺氧微环境刺激肿瘤细胞通过HIF - 1通路产生适应性改变。
Conclusion Tumor is adapted to hypoxic microenvironment through HIF1 pathway after hepatic arterial blockage.
肿瘤细胞的迅速增殖和肿瘤内部新生血管的紊乱使得缺氧成为实体瘤物理微环境的基本特征之一。
Hypoxia is a hallmark of solid tumors, due to the rapid growth of cancer cells and the abnormal angiogenesis within them.
结论：肿瘤局部缺氧和压力变化可以上调MMP - 2、MMP - 9的表达并诱导肿瘤细胞发生LPPCN。
Conclusion: Hypoxia and microenvironment pressure of tumor can increase MMP-2 and MMP-9 expression and influence the LPPCN formation.
结论：肿瘤局部缺氧和压力变化可以上调MMP - 2、MMP - 9的表达并诱导肿瘤细胞发生LPPCN。
Conclusion: Hypoxia and microenvironment pressure of tumor can increase MMP-2 and MMP-9 expression and influence the LPPCN formation.
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