目的研究缬沙坦胶囊生物等效性。
OBJECTIVE To study the bioequivalence of domestic and imported valsartan capsule.
结论:缬沙坦可能具有肾脏保护作用。
结果:缬沙坦与赖诺普利均能有效降低血压。
Results: Both valsartan and lisinopril were effective at lowering blood pressure.
缬沙坦加si是治疗CHF安全有效的药物。
观察缬沙坦对肝硬化患者肝血流动力学的影响。
To study the effect of valsartan on liver hemodynamics in liver cirrhosis patients.
目的:研究国产和进口缬沙坦胶囊的相对生物利用度。
OBJECTIVE To study the relative bioavailability of domestic and imported valsartan capsule.
Exforge禁用于对缬沙坦或氨氯地平敏感患者。
EXFORGE is contraindicated in patients who are hypersensitive to amlodipine or valsartan.
结论:缬沙坦能有效降压并有保护心脏、肾脏的作用。
Conclusion: Valsartan was effective in the treatment of hypertension, and also capable of protecting heart and kidney.
目的观察黄葵胶囊联合缬沙坦治疗糖尿病肾病临床疗效。
Objective To observe clinical therapeutic effect of combination therapy with okra capsule and valsartan for diabetic nephropathy.
结论:国产与进口缬沙坦胶囊的各项质量指标均无明显差异。
CONCLUSIONS: There were no significant differences in quality indexes between the domestic valsartan capsule and the imported one.
目的:探讨缬沙坦对肾性高血压大鼠血管内皮细胞的保护作用。
Objective: To explore the protective effect of valsartan on the vessel endotheliocytes in rats with renal hypertension.
结论缬沙坦能改善向心性重构型原发性高血压患者左室整体舒张功能。
Conclusion Valsartan can improve the global left ventricular diastolic function in essential hypertension patients with left ventricular conventric remodeling.
目的:探讨缬沙坦对2型糖尿病伴高血压左室扩大患者心功能的影响。
Objective: To investigate the effects of Valsartan on cardiac function in patients with Type 2 diabetes and hypertension with the left ventricular dilatation.
目的研究缬沙坦对高血压左室肥厚的逆转作用及对血管活性物质的影响。
ObjectiveTo study the effects of valsartan on reversion of left ventricular hypertrophy(LVH) and vascular active substances in patients with hypertension.
目的:探讨缬沙坦和低分子量肝素对高糖刺激大鼠系膜细胞增殖的影响。
Objective: To observe the effect of valsartan and low molecular weight heparin on the proliferation of glomeruli mesangial cells stimulated by high glucose.
唯一阳性结果是缬沙坦降低糖尿病发病率,尽管有统计学意义,但弱阳性。
The only positive result was a weak, albeit statistically significant, reduction in the incidence of diabetes with valsartan.
目的探讨缬沙坦逆转糖尿病心肌病(DCM)心肌间质纤维化的作用机制。
Objective To investigate the mechanism of reversion of myocardial interstitial fibrosis in diabetic cardiomyopathy (DCM) by valsartan.
目的观察比较缬沙坦与硝苯地平对于高血压患者白蛋白尿及肾功能的疗效。
Objective To study the effects of valsartan and nifedipine on proteinuria and renal function of patients with hypertension.
目的:探讨兔在体左心室肥厚心肌跨室壁复极不均一性的变化及缬沙坦的影响。
Objective: To investigate the changes of transmural repolarization heterogeneity in intact rabbits with left ventricular hypertrophy (LVH) and the effects of valsartan on it.
结论:缬沙坦可能是通过抑制AT 1受体抑制哮喘气道炎症和降低气道反应性。
Conclusion: Valsartan may inhibit airway inflammation and reduce airway responsiveness by suppressing AT1 receptors.
前言:目的:观察血管紧张素受体拮抗剂缬沙坦对肾病综合征大鼠的干预保护作用。
Objective: to observe the role of Angiotensin II receptor antagonist valsartan on kidney of rat with nephrotic syndrome.
目的:探讨肾小管功能损害在早期糖尿病肾病中的意义及缬沙坦干预治疗对其影响。
Objective:To investigate the significance of renal tubular dysfunction in patients with early diabetic nephropathy and the effect of interference treatment of Valsartan.
令人意外的是,缬沙坦未能对心血管疾病产生效果,但却对降低糖尿病发病率其作用。
The finding that valsartan failed to have an effect on either of the cardiovascular-disease outcomes but had a positive effect on the incidence of diabetes is surprising.
目的比较不同剂量缬沙坦,对伴代谢异常高血压病(EH)患者心肾损害的保护作用。
Objective To investigate the effects of valsartan of different doses on the cardio-kidney damages in patients with essential hypertension (EH) by metabolic abnormalities.
对照组用强心苷及利尿药常规治疗,治疗组在常规治疗基础上加用缬沙坦及卡维地洛。
The control group of cardiac glycosides and diuretics conventional treatment group on the basis of conventional therapy plus valsartan and carvedilol.
结论小剂量联合应用缬沙坦和雷米普利提升重要脏器的NO值并抑制高血压心肌重塑。
Conclusion Combined low dose of Valsartan and Ramipril increases NO levels in essential organs and inhibits remodeling of hypertensive myocardium.
缬沙坦对于这些患者而言有无特殊优势,我们可以从中得到什么关于治疗方面的启示吗?
Was there any particular advantage of valsartan on these patients and special treatment perhaps that we can learn?
目的观察缬沙坦降压疗效及对原发性高血压(EH)左心室肥厚(LVH)的逆转作用。
Objective observe the depressing effect of Valsarian and its reversing function to EH and LVH.
目的:观察缬沙坦对2型糖尿病早期肾病相关炎症因子的影响及对糖尿病肾病的保护作用。
Objective: to study the influence of valsartan to correlated inflammatory cytokine in early stage of type 2 diabetic nephropathy and the protection to diabetic nephropathy.
胰岛素抵抗以及缬沙坦作为选择性at 1受体阻断剂,在这种作用机制中起什么作用呢?
Do you think insulin resistance plays a major role in this effect? And what is the role of the AT1 receptor selectivity of valsartan in this effect?
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