• 方法:应用生物信息学分析软件分析SARS冠状病毒S蛋白抗原表位序列设计全新抗原表位编码基因序列构建表达载体并在大肠杆菌中表达基因

    Methods: By analyzing the antigen epitope of SARS-CoV s protein with antigenic peptides prediction software, a new gene was designed, and its expression vector was constructed.

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  • 了解日本血吸虫免疫蛋白基因编码序列结构预测功能

    Learn the coding sequence structure of immunophilin gene of Schistosoma japonicum(Sj )and predict its function.

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  • 结果EVI1编码序列旁边放置了管家基因核糖体结合蛋白1增强区域

    The result is the placement of an enhancing region for the housekeeping gene Ribophorin 1 next to the EVI1 coding sequence.

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  • 从结构上来讲基因包含三个区域称为启动子的调节区域;与其并列编码蛋白质的密码子区域;以及3'端尾部序列

    Structurally, a gene is formed by three regions: a regulatory region called the promoter juxtaposed to the coding region containing the protein sequence, and a “3’ tail” sequence.

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  • 遗传信息进行编码基因——长长的脱氧核糖核酸分子中的不连续片段——把它们序列转录成单线信使核糖核酸分子,核糖核酸成为蛋白质模板

    Genesdiscrete segments of long DNA moleculestranscribe their sequences onto single-strand messenger RNA molecules, which then serve as templates for proteins.

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  • 他们蛋白质目录人类基因序列对应,每个蛋白质与包括编码基因在内基因对应。

    They have tied their catalog into the human genome sequence, connecting each protein to the gene that contains instructions for making it.

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  • 我们身体许多基因控制蛋白质编码基因不同地方时间的开和关,就让基因序列更加复杂了。

    Many genes control when protein-coding genes are turned on and off at different places and times in the body, adding a whole new layer of complexity to the genome.

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  • 2003年,美国国立卫生研究院发布了DNA序列元素百科全书或者说编码而这有助于研究人员对我们剩余基因功能的研究。

    In 2003, the NIH started the Encyclopedia of DNA Elements, or ENCODE, which supports researchers in identifying functions for the rest of our genes.

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  • 细节他们作出结论:可能是遗传获得的非编码DNA序列、而不是基因变异才使得最大部分的转录因子结合位置发生变化。

    This detail led them to conclude that inherited non-coding DNA sequencesnot mutations in genesmay drive the lion's share of differences in where transcription factors attach.

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  • 因此原理蛋白质记录组成DNA分子碱基序列(一基因编码化学字符”)。

    So, in principle, the protein can record the order of the bases (the chemicalletters” that carry the genetic code) which make up the molecule.

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  • 但是覆盖基因大约2%蛋白编码序列

    However, this would cover only the estimated 2% of the human genome that codes for proteins.

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  • 本文中,我们提出一个新的方法,在基因组中确定进化上保守蛋白质编码序列

    In this paper, we present a novel approach to identifying evolutionarily conserved protein-coding sequences in genomes.

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  • 序列分析结果表明,库尔勒香梨分离物外壳蛋白基因582个核苷酸组成编码一个由193个氨基酸组成蛋白质

    The sequence analysis determined that the CP gene of Kuerle pear isolation comprised 582 nucleotides and encoded 193 amino acids containing consensus of nucleotide binding motif.

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  • 研究日本血吸虫亲免素基因编码序列结构及进行初步的功能预测

    To learn the coding sequence structure of immunophilin gene of Shistosoma japonicum(Sj )and predict its funtion.

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  • 这些药物设计为可以激活rna干扰,从而沉默具有药物序列符合编码基因

    The drugs are designed to activate RNA interference to silence a gene with a sequence of letters of the genetic code corresponding to the sequence in the drug.

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  • 因此,CYP86MF基因核苷酸及其可能编码氨基酸序列差异间大,可用于分类等级研究。

    It was concluded that CYP86MF gene was applicable to genus taxon because the differences of sequences in nucleotides and amino acids were lower (between) species than genera.

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  • 实际上包括功能性重要基因,231个编码序列中的83%显示氨基酸序列层次上差异

    Indeed, 83% of the 231 coding sequences, including functionally important genes, show differences at the amino acid sequence level.

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  • 通过氨基酸序列分析发现rxrg基因的该片段10个外子组成,编码463个氨基酸。

    The analysis of amino acid sequence indicated that cattle RXRG gene consisted 10 exons and coded 463 amino acids.

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  • 结果序列比对发现突变位点较多发生UTR区域同时一些基因编码区域也发生蛋白序列变化

    Results it was found by sequence contrast that some mutation sites occurred mainly on UTR region, and a lot of protein sequences changed according to changes of genes coding region.

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  • 细菌基因序列测序工作完成人类分析研究编码细菌毒性蛋白基因认识和阐明毒性蛋白的毒理带来新的机遇

    All those works will bring a new opportunity to study the toxicity gene of coding bacterial toxicity protein, and to understand the toxicology of toxicity protein.

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  • 国内外首次利用抗体探针获得植物抗病蛋白编码基因部分序列进一步克隆全长的API蛋白基因奠定了基础

    It is the first report of obtaining partial sequences of plant disease resistance gene by using antibody probe in the world, which provides a basis of cloning the whole gene encoding API protein.

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  • 编码该酶ADH2基因ADH1ADH3基因基因序列上有94%是一致的。

    The gene of encoded ADH2 is 94% identical with ADH1 and ADH3 in sequence.

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  • 目的不同粘附变形链球菌临床分离表面蛋白V区、P区编码基因进行序列测定。

    Objective: To sequence V-region and P-region gene of surface protein of serotype c Streptococcus mutans clinical isolates with different adherent abilities.

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  • 目的人类基因组中,有98%DNA序列属于编码序列

    Objectives: 98% of DNA sequence in human genome belongs to non-coding sequence.

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  • 看家基因较短编码序列可能提高它们的转录效率自然选择造成的。

    The shorter coding sequences may be a result of natural selection for improved translational efficiency.

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  • 充分考虑装配序列规划过程中所涉及的装配动作、装配夹具装配方向方面因素,采用基因编码方法对装配信息进行编码

    The genetic algorithm adopted the encode method of gene-group, expressed the assembly information of parts such as assembly actions, assembly tools, assembly fixtures and assembly directions, etc.

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  • RNA发现一类编码RNA分子,动植物细胞中广泛表达,基因反向重复序列

    MicroRNAs(miRNA) are a new class of noncoding RNAs, which are encoded as short inverted repeats in the genomes of animals and plants.

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  • 经d NA序列分析表明基因含有全部前导序列成熟蛋白编码部分与从第一骨架引物所克隆的序列相符。

    DNA sequences analysis indicated that the cloned genes included the whole leader sequences and the mature Ig protein encoding regions.

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  • 目的基因dna获取编码源性神经营养因子基因对目的基因进行序列测定。

    Objective: to amplify the gene for human brain - derived neurotrophin factor (BDNF) directly from human genomic DNA and to assure it by sequencing.

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  • 本研究扩增得到的基因片段报道ghrh基因编码序列完全一致

    Homogenious analysis showed that it was consistent with the reported porcine GHRH gene sequence.

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