方法:应用生物信息学分析软件分析SARS冠状病毒S蛋白的抗原表位序列,设计全新的抗原表位编码基因序列,构建表达载体并在大肠杆菌中表达该基因。
Methods: By analyzing the antigen epitope of SARS-CoV s protein with antigenic peptides prediction software, a new gene was designed, and its expression vector was constructed.
了解日本血吸虫免疫蛋白基因的编码序列结构,并预测其功能。
Learn the coding sequence structure of immunophilin gene of Schistosoma japonicum(Sj )and predict its function.
结果是在EVI1编码序列旁边放置了一个管家基因核糖体结合蛋白1的增强区域。
The result is the placement of an enhancing region for the housekeeping gene Ribophorin 1 next to the EVI1 coding sequence.
从结构上来讲,基因包含三个区域:称为启动子的调节区域;与其并列的编码蛋白质的密码子区域;以及3'端尾部序列。
Structurally, a gene is formed by three regions: a regulatory region called the promoter juxtaposed to the coding region containing the protein sequence, and a “3’ tail” sequence.
对遗传信息进行编码。基因——长长的脱氧核糖核酸分子中的不连续的片段——把它们的序列转录成单线信使核糖核酸分子,核糖核酸又成为蛋白质的模板。
Genes — discrete segments of long DNA molecules — transcribe their sequences onto single-strand messenger RNA molecules, which then serve as templates for proteins.
他们已将蛋白质目录与人类基因组序列对应,每个蛋白质与包括编码基因在内的基因对应。
They have tied their catalog into the human genome sequence, connecting each protein to the gene that contains instructions for making it.
在我们身体中许多基因控制着蛋白质编码基因在不同地方和时间的开和关,这就让基因序列更加复杂了。
Many genes control when protein-coding genes are turned on and off at different places and times in the body, adding a whole new layer of complexity to the genome.
在2003年,美国国立卫生研究院发布了DNA序列元素的百科全书或者说编码,而这有助于于研究人员对我们剩余基因功能的研究。
In 2003, the NIH started the Encyclopedia of DNA Elements, or ENCODE, which supports researchers in identifying functions for the rest of our genes.
这一细节让他们作出结论:可能是遗传获得的非编码DNA序列、而不是基因变异才使得最大部分的转录因子结合位置发生变化。
This detail led them to conclude that inherited non-coding DNA sequences – not mutations in genes – may drive the lion's share of differences in where transcription factors attach.
因此,原理上蛋白质能记录下组成DNA分子的碱基序列(一种带着基因编码的化学“字符”)。
So, in principle, the protein can record the order of the bases (the chemical “letters” that carry the genetic code) which make up the molecule.
但是它仅能覆盖人基因组中大约2%的蛋白编码序列。
However, this would cover only the estimated 2% of the human genome that codes for proteins.
在本文中,我们提出了一个新的方法,在基因组中确定进化上保守的蛋白质编码序列。
In this paper, we present a novel approach to identifying evolutionarily conserved protein-coding sequences in genomes.
序列分析结果表明,库尔勒香梨分离物外壳蛋白基因由582个核苷酸组成,编码一个由193个氨基酸组成的蛋白质。
The sequence analysis determined that the CP gene of Kuerle pear isolation comprised 582 nucleotides and encoded 193 amino acids containing consensus of nucleotide binding motif.
研究日本血吸虫亲免素基因编码序列的结构及进行初步的功能预测。
To learn the coding sequence structure of immunophilin gene of Shistosoma japonicum(Sj )and predict its funtion.
这些药物设计为可以激活rna干扰,从而沉默具有与药物序列相符合的编码的基因。
The drugs are designed to activate RNA interference to silence a gene with a sequence of letters of the genetic code corresponding to the sequence in the drug.
因此,CYP86MF基因的核苷酸及其可能编码的氨基酸序列差异属间较种间大,它可用于属间的分类等级研究。
It was concluded that CYP86MF gene was applicable to genus taxon because the differences of sequences in nucleotides and amino acids were lower (between) species than genera.
实际上,包括功能性重要基因,231个编码序列中的83%显示了在氨基酸序列层次上的差异。
Indeed, 83% of the 231 coding sequences, including functionally important genes, show differences at the amino acid sequence level.
通过氨基酸序列分析发现,牛rxrg基因的该片段由10个外显子组成,编码463个氨基酸。
The analysis of amino acid sequence indicated that cattle RXRG gene consisted 10 exons and coded 463 amino acids.
结果经序列比对发现突变位点较多发生在UTR区域,同时一些基因的编码区域也发生蛋白序列的变化。
Results it was found by sequence contrast that some mutation sites occurred mainly on UTR region, and a lot of protein sequences changed according to changes of genes coding region.
细菌全基因组序列测序工作的完成将给人类分析和研究编码细菌毒性蛋白的毒力基因、认识和阐明毒性蛋白的毒理带来新的机遇。
All those works will bring a new opportunity to study the toxicity gene of coding bacterial toxicity protein, and to understand the toxicology of toxicity protein.
在国内外首次利用抗体探针获得了植物抗病蛋白编码基因的部分序列,为进一步克隆全长的API蛋白基因奠定了基础。
It is the first report of obtaining partial sequences of plant disease resistance gene by using antibody probe in the world, which provides a basis of cloning the whole gene encoding API protein.
编码该酶的ADH2基因与ADH1和ADH3基因在基因序列上有94%是一致的。
The gene of encoded ADH2 is 94% identical with ADH1 and ADH3 in sequence.
目的:对不同粘附力变形链球菌临床分离株表面蛋白V区、P区编码基因进行序列测定。
Objective: To sequence V-region and P-region gene of surface protein of serotype c Streptococcus mutans clinical isolates with different adherent abilities.
目的:在人类基因组中,有98%的DNA序列属于非编码序列。
Objectives: 98% of DNA sequence in human genome belongs to non-coding sequence.
看家基因有较短的编码序列可能是为提高它们的转录效率自然选择造成的。
The shorter coding sequences may be a result of natural selection for improved translational efficiency.
充分考虑在装配序列规划过程中所涉及到的装配动作、装配工夹具与装配方向等各方面因素,采用基因组的编码方法对装配信息进行编码;
The genetic algorithm adopted the encode method of gene-group, expressed the assembly information of parts such as assembly actions, assembly tools, assembly fixtures and assembly directions, etc.
微RNA是新发现的一类非编码RNA分子,在动植物细胞中广泛表达,它的基因是短的反向重复序列。
MicroRNAs(miRNA) are a new class of noncoding RNAs, which are encoded as short inverted repeats in the genomes of animals and plants.
经d NA序列分析表明所获基因含有全部前导序列,其成熟蛋白编码部分与从第一骨架区引物所克隆的序列相符。
DNA sequences analysis indicated that the cloned genes included the whole leader sequences and the mature Ig protein encoding regions.
目的:从基因组dna获取编码脑源性神经营养因子基因,并对目的基因进行序列测定。
Objective: to amplify the gene for human brain - derived neurotrophin factor (BDNF) directly from human genomic DNA and to assure it by sequencing.
本研究扩增得到的基因片段与报道的猪ghrh基因编码区序列完全一致。
Homogenious analysis showed that it was consistent with the reported porcine GHRH gene sequence.
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