方法采用流化床包衣法制得缓释微丸，将微丸压片后包衣制得时控脉冲缓释片。
METHODS To prepare sustained release pellets using fluid bed, then to get pulsatile-sustained tablet after tabletting and coating.
本文采用流化床技术制备盐酸二甲双胍素丸，并采用缓释包衣材料制备缓释盐酸二甲双胍微丸。
In this thesis, Metformin Hydrochloride pellets and sustained-release pellets were prepared by powder coating technology.
以丙烯酸树脂RL 100为包衣材料，采用乳剂-溶剂挥发法，制备了以药物-树脂为丸芯的缓释微丸。
By in-liquid drying, sustained-release pellets were prepared taking Eurdragit RL100 as coating material and drug-resin complex as core.
以丙烯酸树脂RL 100为包衣材料，采用乳剂-溶剂挥发法，制备了以药物-树脂为丸芯的缓释微丸。
By in-liquid drying, sustained-release pellets were prepared taking Eurdragit RL100 as coating material and drug-resin complex as core.
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