本给药系统在“漏槽”状态下测定释放速度，经短时间的较快释放后可维持长期的零级速度。
After a initial transient, "burst effect", the drug was released continuously from the device at a constant rate for a long period of time.
近年来，SLN的口服和经皮给药逐渐受到重视，研究发现，口服经过SLN包裹后的药物能降低其血药浓度峰值，并延长药物作用时间。
Only recently have the peroral or dermal use been evaluated. Drugs encapsulated into SLN showed a reduced peak plasma concentration and prolonged therapeutic drug level following oral administration.
结果珍珠滴丸给药后可明显缩短大鼠口腔黏膜溃疡50%愈合时间。
Results The pearl drop pills can obviously shorten 50% concrescence time of rats oral ulcer.
给药后的不同时间间隔从前腔静脉采血，用微生物法测定血清青霉素G的浓度。
Blood samples were collected from the superior vena cava at different intervals after the drug was given. Serum levels of penicillin G were determined by microbiological method.
方法建立小鼠系统性白念珠菌感染模型，观察给药后小鼠中位生存时间，并检测给药后小鼠肾脏菌落形成单位计数。
Methods a mouse model of disseminated candidiasis was established and the survival rate and median survival time after administration of agent were detected.
观察微丸外观性状并计数，计算给药后不同时间点其在各段消化道的分布率；
The appearance of pellets were observed. The sum of pellets and the distribution rates in different sections of alimentary canal were counted.
腹腔给药后能显著延长荷瘤鼠的生存时间，含药微球组和空白微球组生命延长率分别为153.49%和142.22%。
It significantly prolonged the survival time of mice with H22 ascites HCC and the increased life span by 153.49% and 142.22% when EPI-PLA-MS were intraperitoneally administered.
从脑片染色结果及给药后不同时间点大鼠血液中纤溶酶原激活剂和其抑制剂的含量变化显示用该工艺纯化的蚓激酶有较好的溶栓作用。
The EFE purified through the process mentioned above has high specific activity and good effect in treating cerebral ischemia. Concerntration oft-PA and PAI, in respect of the rats in…
从脑片染色结果及给药后不同时间点大鼠血液中纤溶酶原激活剂和其抑制剂的含量变化显示用该工艺纯化的蚓激酶有较好的溶栓作用。
The EFE purified through the process mentioned above has high specific activity and good effect in treating cerebral ischemia. Concerntration oft-PA and PAI, in respect of the rats in…
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