在经皮给药系统中,脂质体是一种极具前途的给药载体。
It was suggested that liposome is a promising carrier for trans dermal drug delivery system.
摘要目的:寻找以聚丙烯酸酯为骨架的睾酮经皮给药系统的最佳处方。
ABSTRACT OBJECTIVE: to search after the optimum formulation of the TDS of testosterone. METHOD: Various formations whose skeleton was polyacrylic acid were designed.
许多新方法和新技术的应用,使经皮给药系统逐渐成为一种成熟的给药方法。
With utilities of new methods and techniques, TDDS is becoming a mature method.
结果表明,该聚氨酯压敏胶贴剂具有良好的药物控释能力,适用于经皮给药系统。
The results indicated that the hydrophilic polyurethane PSA prepared show good transdermal drug release properties, which suit for the TDDs application.
目的由于皮肤的屏障作用,经皮给药系统的应用受到限制,促透方法的研究成为焦点。
Because of the barrier of skin, the application of transdermal delivery system is limited. It is very important to study enhancement methods of drug percutaneous absorption.
结论:1,2 -丙二醇,月桂氮卓芯酮—胰岛素传递体经皮给药系统可进一步提高胰岛素传递体的透皮吸收效率,降低血糖。
CONCLUSION Transfersulin system with azone and 1, 2-propanediol can improve the penetration efficiency on mice skin and eliminate the blood glucose.
本文针对经皮给药系统新型压敏胶及新型经皮给药技术需求,研制了三类亲水性压敏胶及两种药物纳米载体材料,并对其性能进行了研究。
In this study, three kinds of hydrophilic pressure sensitive adhesives and two kinds of nanocarrier materials were prepared for technology requirement of TDDS and their properties were investigated.
药物的初始释放速率和传统经皮给药控释系统相近,释药量与储库层药物含量无关;
The release rate of composite patches was similar to that of traditional patches at the beginning but was larger on average.
本文的目的是对抗疟药青蒿素的经皮给药进行系统设计和确定青蒿素贴剂的制备工艺。
The purpose of this study was to investigate a transdermal delivery system of antimalarial drug: artemisinin.
结论优化条件制备出的补骨脂素皮肤用纳米粒载药系统有可能成为临床上改进补骨素光化学疗法降低其毒副作用的一种新的经皮给药制剂。
CONCLUSION Psoralen loaded PLGA nanospartilcles might be a promising transdermal delivery system in order to improve the efficacy and reduce the side effects in the PUVA therapy.
结论优化条件制备出的补骨脂素皮肤用纳米粒载药系统有可能成为临床上改进补骨素光化学疗法降低其毒副作用的一种新的经皮给药制剂。
CONCLUSION Psoralen loaded PLGA nanospartilcles might be a promising transdermal delivery system in order to improve the efficacy and reduce the side effects in the PUVA therapy.
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