结论双氯芬酸二乙胺盐凝胶经皮给药安全。
Conclusion Diclofenac diethylamine salt gel is safe for transdermal administration.
目的:探讨经皮给药治疗小儿病毒性肠炎的临床疗效。
Objective: To explore the clinical effect of dermal medication on children virus enteritis.
在经皮给药系统中,脂质体是一种极具前途的给药载体。
It was suggested that liposome is a promising carrier for trans dermal drug delivery system.
目的考察醇质体作为非那甾胺经皮给药载体的渗透特性。
OBJECTIVE To investigate the penetration characteristics of finasteride ethosomes as a transdermal vehicle.
结论作为经皮给药的载体,醇质体有良好的应用前景和开发价值。
Results Ethosomal system with good fluidity, deformability and high trapping rate is a stable carrier for transdermal delivery.
目的探讨神厥穴经皮给药对腹部手术后患者胃肠功能恢复的影响。
Objective to explore the effect of percutaneous drug administration to Shenjue points on facilitating gastrointestinal function recovery among patients undergoing abdominal operation.
摘要目的:寻找以聚丙烯酸酯为骨架的睾酮经皮给药系统的最佳处方。
ABSTRACT OBJECTIVE: to search after the optimum formulation of the TDS of testosterone. METHOD: Various formations whose skeleton was polyacrylic acid were designed.
目的研究胰岛素柔性脂质体的制备及其对正常小鼠经皮给药的降血糖效果。
OBJECTIVE The study was undertaken to prepare the flexible lecithin liposomes containing insulin and to investigate the transdermal enhancing effect of flexible liposomes on insulin.
许多新方法和新技术的应用,使经皮给药系统逐渐成为一种成熟的给药方法。
With utilities of new methods and techniques, TDDS is becoming a mature method.
目的制备秋水仙碱醇质体并考察醇质体作为秋水仙碱经皮给药载体的可行性。
OBJECTIVE To prepare ethosomes and investigate the feasibility of ethosome as transdermal carries of colchicines.
结果表明,该聚氨酯压敏胶贴剂具有良好的药物控释能力,适用于经皮给药系统。
The results indicated that the hydrophilic polyurethane PSA prepared show good transdermal drug release properties, which suit for the TDDs application.
药物的初始释放速率和传统经皮给药控释系统相近,释药量与储库层药物含量无关;
The release rate of composite patches was similar to that of traditional patches at the beginning but was larger on average.
经皮给药制剂是一种有着广阔市场前景的给药途径,但皮肤使多数药物难以渗透吸收。
Transdermal drug delivery systems (TDDS) have broad market prospects. However, transdermal delivery is limited by the inability of the large majority of drugs to cross skin.
目的由于皮肤的屏障作用,经皮给药系统的应用受到限制,促透方法的研究成为焦点。
Because of the barrier of skin, the application of transdermal delivery system is limited. It is very important to study enhancement methods of drug percutaneous absorption.
本文的目的是对抗疟药青蒿素的经皮给药进行系统设计和确定青蒿素贴剂的制备工艺。
The purpose of this study was to investigate a transdermal delivery system of antimalarial drug: artemisinin.
经皮给药是将药物贴敷在皮肤外表面,依靠被动扩散或促进扩散使药物通过皮肤进入皮下毛细血管。
TDD is the method that patching the drug on the skin, the drug molecules permeating through the skin into the subcutaneous capillary vessels by passive diffusion and enhanced diffusion.
目的:探讨穴位经皮给药对慢性支管炎的疗效及该方法对慢性支气管炎中热痰型与寒痰型的疗效比较。
Objective:To study the curative effect of point application to chronic bronchitis and the comparison between heat-phlegm and cold-phlegm.
结论:1,2 -丙二醇,月桂氮卓芯酮—胰岛素传递体经皮给药系统可进一步提高胰岛素传递体的透皮吸收效率,降低血糖。
CONCLUSION Transfersulin system with azone and 1, 2-propanediol can improve the penetration efficiency on mice skin and eliminate the blood glucose.
传统的被动式经皮给药严重受限于皮肤角质层的阻碍,利用微针阵列破坏角质层可改善皮肤对药物的渗透性,大大提高经皮给药效率。
By disrupting the stratum corneum structure and create pathways allowing transport of macromolecules, microneedles array can improve the transdermal drug delivery and increase the efficiency.
近年来,SLN的口服和经皮给药逐渐受到重视,研究发现,口服经过SLN包裹后的药物能降低其血药浓度峰值,并延长药物作用时间。
Only recently have the peroral or dermal use been evaluated. Drugs encapsulated into SLN showed a reduced peak plasma concentration and prolonged therapeutic drug level following oral administration.
本文针对经皮给药系统新型压敏胶及新型经皮给药技术需求,研制了三类亲水性压敏胶及两种药物纳米载体材料,并对其性能进行了研究。
In this study, three kinds of hydrophilic pressure sensitive adhesives and two kinds of nanocarrier materials were prepared for technology requirement of TDDS and their properties were investigated.
结论优化条件制备出的补骨脂素皮肤用纳米粒载药系统有可能成为临床上改进补骨素光化学疗法降低其毒副作用的一种新的经皮给药制剂。
CONCLUSION Psoralen loaded PLGA nanospartilcles might be a promising transdermal delivery system in order to improve the efficacy and reduce the side effects in the PUVA therapy.
目的:研究经皮肺穿刺给药治疗耐多药空洞型肺结核的临床疗效。
Objective:to explore the clinical effects of perfusing chemotherapy by percutaneous lung puncture in the treatment of multi-drug resistent cavitary pulmonary tuberculosis(MDR-TB).
本发明所述的药物剂型包括各种口服、注射、腔道、经皮等不同给药途径的药物制剂。
The pharmaceutical preparation comprises various preparations in different administration routes, such as oral taking, injection, cavity taking, subcutaneous injection, and the like.
结论胰岛素经皮电渗较胰岛素皮下注射给药吸收速度慢,两种给药方法胰岛素的消除过程相近。
CONCLUSION the absorption rate in the subcutaneous injection group was faster than the three groups of transdermal delivery, but the elimination was the same in all the groups.
经皮穴位给药;
经皮穴位给药;
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