方法应用肠道细菌毒力和侵袭力检测、宋内菌大质粒DNA图谱分析和猴体口服耐受试验对S7株、S7R株进行安全性和稳定性分析。
Methods Making use of enterobacterial virulence and invasive test, DNA profile analysis and challenge test of rhesus monkey to determine the safety and stability of S7 and S7R.
如由噬菌体介导的细菌毒力基因的转移、细菌耐药基因的传递等导致了病原菌基因表型的多态性，这在医学与遗传学中是一个日益严峻的重要问题。
For example, transfer of virulence gene and transmission of drug-resistant gene mediated by a phage results in gene polymorphism of bacteria, which is an important problem in medicine and genetics.
科学家很久以来就知道在太空细菌和病毒的繁殖会更迅速毒力会更强。
Scientists have long known that bacteria and viruses grow more rapidly and virulently in space.
许多细菌包括病原微生物可进入这一状态并保持毒力或致病性。
Many bacteria including some pathogens can enter this state and maintain virulence or pathogenicity.
以比较基因组学为研究手段，细菌进化基因组学可从基因组水平深入认识物种分化、生境适应、毒力进化、耐药性产生蔓延等表型进化过程。
It is the time to call for evolutionary genomics which probe into bacterial diversity, niche adaptation, virulence evolution, and drug resistance from the view of whole genome.
此外，研究还表明细菌的毒力与鱼的体温也有关系。
In addition, the study shows that the pathogenicity of the bacteria is affected by the body temperature of fish.
细菌全基因组序列测序工作的完成将给人类分析和研究编码细菌毒性蛋白的毒力基因、认识和阐明毒性蛋白的毒理带来新的机遇。
All those works will bring a new opportunity to study the toxicity gene of coding bacterial toxicity protein, and to understand the toxicology of toxicity protein.
结论：细菌的毒力与生物表型密切相关。
Conclusion: The virulence of Shigella is associate with biology phenotypes of Shigella.
生物膜内细菌之间存在的信号传导对生物膜的形成及其毒力具有影响。
The signal transduction existed between the bacterium has an important effect on the formation and virulence of bacterial biofilm.
毒力是指细菌致病性(损害或严重)的程度及其快速侵入宿主组织的能力。
Virulence is the degree of pathogenicity (harmfulness or severity) of the bacteria and its ability to rapidly invade the tissues of the host.
我们简要介绍志贺菌属细菌的毒力检测方法。
This article is a review about how to detect the virulence of the Shigella.
我们简要介绍志贺菌属细菌的毒力检测方法。
This article is a review about how to detect the virulence of the Shigella.
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