研究人员决定研究骨钙素(造骨细胞产生的蛋白质)的作用。
The researchers decided to examine the role of osteocalcin, a protein produced by osteoblasts.
组织,细胞质蛋白,人肿瘤,骨。
骨形成蛋白能抑制人类脑部肿瘤起始细胞的致瘤潜能。
Bone morphogenetic proteins inhibit the tumorigenic potential of human brain tumour - initiating cells.
目的探索从骨肉瘤细胞条件培养基中提取骨形态蛋白(BMP)的方法,并测定其生物学活性。
Objective: To find out a method of extraction and purification of bone morphogenetic protein (BMP) from osteosarcoma cell conditioned medium, and evaluate the biological activity of BMP.
目的探索从骨肉瘤细胞条件培养基中提取骨形态蛋白(BMP)的方法,并测定其生物学活性。
Objective: To find out a method of extraction and purification of bone morphogenetic protein (BMP) from osteosarcoma cell conditioned medium, and evaluate the biological activity of BMP.
目的:探讨骨形成蛋白(BMP)与细胞凋亡的关系及意义。
Aim: to elucidate the relationship between Bone Morphogenetic Protein (BMP) and cell apoptosis.
目的观察兔骨髓诱导的内皮细胞用纤维蛋白胶接种到骨组织工程支架上,在体外人工骨血管化效果。
Objective To observe angiogenesis of induced endothelial cells in demineralized bone matrix scaffold seed by fibrin sealant in vitro.
目的应用荧光蛋白标记技术对组织工程骨体外构建过程进行细胞示踪。
Objective to use the new technique of seeding cells labeled with fluorescent protein for monitoring the construction process of tissue-engineering bone in vitro.
目的观察慢性氟中毒对小鼠切牙成釉细胞骨形成蛋白- 2 (BMP - 2)表达的影响,探讨氟斑牙的致病机制。
Objective To investigate the expression of BMP-2 in mice incisor enamel organ cells under chronic fluoride exposure and elucidate the mechanism of dental fluorosis.
骨桥蛋白是骨和牙的细胞外基质的主要成分,它的作用一直被认为是能通过多种受体来刺激细胞的活性。
Osteopontin is a protein that is a prominent part of the extracellular matrices of bones and teeth. It is known for its ability to stimulate cell activity through multiple receptors.
目的:建立骨唾液蛋白的稳定表达乳腺癌细胞系,观察骨唾液蛋白在乳腺癌骨转移的整个过程中的作用。
OBJECTIVE: To establish breast cancer cell strains of BSP with stable expression and observe the effect of BSP in the whole process of breast cancer bone metastasis.
细胞对同种异体骨的附加作用并不能促进愈合,除非有使骨形态发生蛋白2表达的基因修改。
The addition of bone marrow-derived cells to an allograft does not improve healing unless they are genetically modified to express bone morphogenetic protein 2.
目的制备脱细胞松质骨作为骨形态发生蛋白2 (BMP - 2)载体,观察其异位成骨状况。
Objective to prepare acellular cancellous bone as carrier for bone morphogenetic protein 2 (BMP-2), and observe the ectopic osteogenesis.
目的:探索从人骨肉瘤细胞条件培养基中提取骨形态蛋白(BMP)的方法,并测定其生物学活性。
Objective :To find out a method of extraction and purification of bone morphogenetic protein (BMP) from the conditioned medium of human osteosarcoma cell, and evaluate its biological activity.
骨吸收功能短暂激活,主要表现为:破骨细胞数量一度增加,而其泌酸和蛋白酶功能基本得以保持。
The transient activation of bone resorption function, presented as the temporary increase of osteoclasts number and mostly maintenance of its function of excreting acid and protease.
目的:研究成骨生长肽OGP在体外对大鼠颅盖骨成骨细胞I型胶原蛋白的影响。
Objective:To elucidate the effect of osteogenic growth peptide(OGP) on the collagen I in cultured rat osteoblast-like cells.
目的:应用纤维蛋白胶作为细胞支架进行兔骨髓基质细胞立体培养,探讨其作为新型骨组织工程支架材料的可行性。
AIM: to observe three-dimensional culture of rabbit marrow stromal cells (MSCs) in fibrin glue in vitro, and discuss the feasibility of the fibrin glue to be use as a kind of scaffold material.
依靠蛋白质的作用,靶细胞被刺激分化,通过自分泌或旁分泌的方式促进成骨。
Depend on the role of proteins, target cells were stimulated differentiation by an autocrine or paracrine manner to promote osteogenesis.
骨形态发生蛋白(BMP)是一类具有高效成骨活性的蛋白质,因其能够异位诱导间充质细胞分化为软骨和骨细胞而形成新骨,在临床骨缺损修复中具有良好的应用前景。
Bone morphogenetic protein (BMP) has good potential in treatment for bone defects as it can induce mesenchymal cells to differentiate into cartilage cells and bone cells so to form new bone.
目的观察兔骨髓诱导的内皮细胞用纤维蛋白胶接种到骨组织工程支架上,在体外人工骨血管化效果。
Objective To observe angiogenesis of induced endothelial cells(ECs) in demineralized bone matrix scaffold seed by fibrin sealant in vitro.
目的通过检测特发性身材矮小(ISS)儿童血清骨碱性磷酸酶(BAP)及骨钙蛋白(OC)水平,探讨其成骨细胞的功能状况。
Objective To detect serum bone specific alkaline phosphatase (BAP) and osteocalcin (oc) in children with idiopathic short stature (ISS), and explore the status of osteoblast.
此外,骨分化相关特征基因骨桥蛋白OPN在复合支架上培养的细胞中的表达水平也明显高于纯壳聚糖上培养的细胞。
Simultaneously, the osteogenic gene osteopon tin(OPN)of cells cultured on composite scaffolds showed a higher expression level than that on chitosan scaffolds.
骨桥蛋白是一种具有多种功能的磷酸化糖蛋白,不仅广泛分布于骨基质等正常组织细胞中,而且在许多肿瘤组织中都过量表达。
Osteopontin is a multifunctional phosphoglycoprotein. It not only distribute widely in normal tissues such as bone tissues, but also has over expression in multiplicate tumor tissues.
目的探讨癌基因蛋白表达在骨巨细胞瘤生物学行为与预后方面的意义。
Objective to study the correlation of expression of oncogene proteins with the invasion and recurrence of giant cell tumor (GCT) of bone and its various cytologic grades.
骨性节炎软骨细胞直接分泌到胞外的金属蛋白酶含量变化不明显;
The variance of MMPs'content in ECM of OA chondrocytes of rabbits secretion was not significant.
它诱导细胞周期停滞在G1期晚期,可能诱导成骨蛋白2 (BMP - 2)。
It induces cell cycle arrest in late G1 phase and may induce bone morphogenic protein-2 (BMP-2).
鹿茸多肽可促进骨性关节炎软骨细胞增殖,并可抑制骨性关节炎软骨细胞中金属蛋白酶的过度表达,可能对治疗骨性关节炎有较好的作用。
Pilose antler peptide can promote the proliferation of OA chondrocytes of rabbits , inhibit the overexpression of MMPs of OA chondrocytes. It can possibly play a effective role in the treatment of OA.
重组人酸性成纤维细胞生长因子和纤维蛋白载体再生骨。
Recombinant human acidic fibroblast growth factor and fibrin carrier regenerates bone.
结论:釉基质蛋白可作为一种成骨诱导剂,能有效增强大鼠脂肪源性干细胞体外增殖活性并诱导其成骨分化。
Conclusion: Enamel matrix proteins may be used as an osteoinductive agent, due its enhancing effect on adipose-derived stem cells proliferation and osteogenic differentiation.
结论:釉基质蛋白可作为一种成骨诱导剂,能有效增强大鼠脂肪源性干细胞体外增殖活性并诱导其成骨分化。
Conclusion: Enamel matrix proteins may be used as an osteoinductive agent, due its enhancing effect on adipose-derived stem cells proliferation and osteogenic differentiation.
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